RetS-mediated environmental sensing coordinates TetR-dependent regulation of type III secretion system and virulence in Pseudomonas syringae pv. actinidiae [0.03%]
RetS介导的环境感受调控Pseudomonas syringae pv. actinidiae中TetR依赖型III型分泌系统和致病岛相关毒力基因表达
Renjian Hu,Fu Zhao,Muhammad Asif et al.
Renjian Hu et al.
Kiwifruit bacterial canker, caused by Pseudomonas syringae pv. actinidiae (Psa), is an emerging global concern in kiwifruit production. Successful Psa infection in kiwifruit relies on the type III secretion system (T3SS), which is governed ...
Evaluating Type III Secretion System Genes (escE, esaE and eseJ) of Edwardsiella piscicida for Virulence in Japanese Flounder (Paralichthys olivaceus) [0.03%]
评估Escherichia piscicida的III型分泌系统基因（escE，esaE和eseJ）在日本豆腐鱼（Paralichthys olivaceus）中致病性方面的作用
Yasuhiko Kawato,Takamitsu Sakai,Yukihiro Nakagawa et al.
Yasuhiko Kawato et al.
Edwardsiella piscicida, an etiological agent of edwardsiellosis in finfish, causes severe damage to the aquaculture industry in the world. The virulence of E. piscicida is known to be associated with the type III secretion system (T3SS) whi...
Highly efficient degradation of herbicide in the Ti/PbO2-Bi anode/stainless-steel pad cathode/ electro-activated persulfate oxidation system: Effective factors, degradation pathway and toxicity assessment [0.03%]
Ti/PbO2-Bi阳极/不锈钢阴极/电活化过硫酸盐氧化系统中降解除草剂的高效性：有效因素、降解路径和毒性评估
Abdulaziz Ibrahim Almohana,Sattam Fahad Almojil
Abdulaziz Ibrahim Almohana
The present study aims to improve the degradation and reduce the toxicity of the degradation-resistant DIU herbicide in the synergistic process of anodic oxidation/electro-activation of persulfate (EPS). Anodic oxidation was performed on a ...
Mechanism and marker of voriconazole-induced liver injury: insights from a quantitative systems toxicology approach [0.03%]
伏立康唑致肝损伤的发生机制及标志物：定量系统毒理学方法的启示
Qian Du,Yulan Qiu,Luting Yang et al.
Qian Du et al.
Liver injury severely limits the clinical use of voriconazole. Clarifying the mechanism and markers of voriconazole-induced liver injury is of great significance. In this study, a quantitative systems toxicology model of voriconazole-induce...
Phosphate perils in marine aquaculture: Systematic toxicity assessment in turbot juveniles in cultivation [0.03%]
海洋养殖中的磷酸盐危害——多宝鱼幼鱼系统毒性评估
Lele Wu,Xin Li,Jiale Zhou et al.
Lele Wu et al.
Recirculating Aquaculture Systems (RAS) aim to minimize water usage while maintaining optimal conditions for aquatic organisms, which is increasingly recognized as a crucial strategy for advancing sustainable aquaculture practices and enhan...
Integration of Animal, Population, and Toxicogenomic Evidence on the Hematotoxic and Immunosuppressive Effects of Environmental Exposure to PFAS Mixtures in Adolescents [0.03%]
动物、人群和毒基因组学证据在环境多氟烷基物质混合物暴露对青少年血液系统毒性及免疫抑制作用方面的综合分析
Xiushuai Du,Xueming Xu,Xing-Xuan Dong et al.
Xiushuai Du et al.
Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are emerging contaminants widely found in drinking water and food, potentially entering the human body through these sources. To investigate these effects, we simulated PFAS exposure dos...
External Validation of STopTox - Novel Alternative Method (NAM) for Acute Systemic and Topical Toxicity [0.03%]
STopTox-NAM急性系统毒性和局部毒性替代方法的外部验证
Ricardo Scheufen Tieghi,Cleber C Melo-Filho,Holli-Joi Martin et al.
Ricardo Scheufen Tieghi et al.
Osimertinib-chemotherapy synergy in EGFR-mutant NSCLC: advancing central nervous system control amidst toxicity considerations [0.03%]
奥希替尼联合化疗在EGFR突变型非小细胞肺癌中的协同作用：在考虑毒性的情况下控制中枢神经系统病变的进展
Rahul Kumar,Emily Miao,Luke Roy George Pike
Rahul Kumar
Validation of a procedure for toxicants detection in baits and animal organs in case of suspected poisoning by using GC-MS and LC-MS/MS, as a part of systematic toxicological analysis based on 15 years of experience [0.03%]
基于15年经验的系统毒理学分析中，疑似中毒时使用GC-MS和LC-MS/MS检测诱饵和动物器官中毒物的方法验证
Claudia Focardi,Giulia Biancalani,Gerardina Marmo et al.
Claudia Focardi et al.
The aim of this study was to describe a Systematic Toxicological Analysis (STA) procedure adopted for the determination of toxicants in baits or samples derived from suspected poisoned animals. Extraction and purification were based on a Qu...
A possible approach to overcome the systemic toxicity of azathioprine (AZA) through nanoemulgel [0.03%]
一种通过纳米乳凝胶克服硫唑嘌呤系统毒性的潜在方法
Bikash Kumar Sah,Faiz Ahmad,Sachin Kumar Singh et al.
Bikash Kumar Sah et al.
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