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Tao Du,Qing Zhang Tao Du
Aim: The pathogenesis of diabetic kidney disease (DKD) is complex, and the specific biomarkers for detecting early diagnosis and monitoring kidney function deterioration are insufficient, which affects the prognosis of pa...
Yan Miao,Lei Yan,Huixia Cao et al. Yan Miao et al.
Background: Diabetic nephropathy (DN) is a major cause of kidney failure, and its incidence is increasing worldwide. Existing studies have shown that mitochondrial dysfunction is potentially related to the pathogenesis of...
Yuejia Tao,Yipeng Liu,Zunsong Wang et al. Yuejia Tao et al.
Objective: We employed bioinformatics to identify potential biomarkers for diabetic nephropathy (DN) and investigate the role of the key gene lumican in its molecular processes. ...
Ersilia Satta,Felice Strollo,Luisa Borgia et al. Ersilia Satta et al.
Patients with diabetes mellitus (DM) are at risk of developing diabetic nephropathy (DN), a condition whose onset and progression are linked to increased morbidity and mortality. Therefore, early recognition is crucial. Presently, this reli...
Miao Hu,Yi Deng,Yujie Bai et al. Miao Hu et al.
Background: Renal failure related death caused by diabetic kidney disease (DKD) is an inevitable outcome for most patients. This study aimed to identify the critical genes involved in the onset and progression of DKD and ...
Qin Li,Yafei Xie,Meiying Zuo et al. Qin Li et al.
Background: Diabetic nephropathy (DN) is a common complication of diabetes, which is prone to develop into end-stage renal disease, and early diagnosis and treatment is the key to effective management of DN. Biomarkers ha...
Sha Li,Jingshan Chen,Wenjing Zhou et al. Sha Li et al.
Propionate metabolism is important in the development of diabetes, and fibrosis plays an important role in diabetic nephropathy (DN). However, there are no studies on biomarkers related to fibrosis and propionate metabolism in DN. Hence, th...
Yidong Zhu,Jun Liu,Bo Wang Yidong Zhu
Aim: To identify potential biomarkers and explore the mechanisms underlying diabetic nephropathy (DN) by integrating machine learning, Mendelian randomization (MR) and experimental validation. ...
Fatih Yay,Ergül Bayram,Hunkar Aggul et al. Fatih Yay et al.
Aims: We aimed to examine the role of circulating immature granulocytes (IGs) in assessing Diabetic Nephropathy (DN) mainly and also associations of other leukocyte parameters with DN. ...
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