Dopaminergic neurons in the ventral periaqueductal gray projecting to the dorsal lateral septum regulate comorbid pain and anxiety [0.03%]
伏隔核多巴胺能神经元投射至背外侧 septum参与共病痛和焦虑的调节
Shaoshan Wang,Yani Guo,Bingdi Wei et al.
Shaoshan Wang et al.
The comorbidity of pain and anxiety is one of the most prevalent mental health disorders globally. However, its underlying etiological mechanisms remain incompletely understood. This study revealed that the dorsal lateral septum (LSD) and i...
Whole-brain mapping of basal forebrain cholinergic neurons reveals a long-range reciprocal input-output loop between distinct subtypes [0.03%]
全脑基底前脑胆碱能神经元投射图谱揭示了不同类型胆碱能神经元之间的长程相互连接的输入输出回路
Zhaonan Chen,Yanmei Liu,Yunqi Yang et al.
Zhaonan Chen et al.
Basal forebrain cholinergic neurons (BFCNs) influence cognition and emotion through specific acetylcholine release in various brain regions, including the prefrontal cortices and basolateral amygdala (BLA). Acetylcholine release is controll...
Biyu Ren,Xiaoxue Shi,Bingqing Zhao et al.
Biyu Ren et al.
Reconstructing single-neuron projectomes is essential for mapping the mesoscopic connectome and eventually for understanding brain-wide connectivity and diverse brain functions. The combination of sparse labeling techniques and large-scale ...
Fumino Fujiyama,Fuyuki Karube
Fumino Fujiyama
Environmental adaptation requires reward prediction errors to be transmitted to the striatum by dopaminergic neurons in the substantia nigra pars compacta of the midbrain. Various methods have been used to visualize the neural circuits invo...
Projections from ventral hippocampus to nucleus accumbens' cholinergic neurons are altered in depression [0.03%]
抑郁症患者来自腹侧海马到伏隔核的胆碱能神经元投射发生改变
Lucian Medrihan,Margarete G Knudsen,Tatiana Ferraro et al.
Lucian Medrihan et al.
The cholinergic interneurons (ChIs) of the nucleus accumbens (NAc) have a critical role in the activity of this region, specifically in the context of major depressive disorder. To understand the circuitry regulating this behavior, we sough...
Dynorphinergic lateral hypothalamus to posterior ventral tegmental area pathway matures after adolescence in male rats [0.03%]
大鼠青春期后外侧下丘脑 dynorphin 能神经元投射至腹中脑背侧核簇状部的环路成熟发育特征（仅限雄性大鼠）
Alexandra Rogers,Emily M Castro,Shahrdad Lotfipour et al.
Alexandra Rogers et al.
The highly plastic nature of the adolescent brain is well-known, and is thought to contribute to the unique susceptibility of adolescents to drugs of abuse. However, much investigation of adolescent plasticity has been focused on synaptic p...
Supraspinal facilitation of painful stimuli by glutamatergic innervation from the retrosplenial to the anterior cingulate cortex [0.03%]
后扣带回皮层谷氨酸能神经元投射至前扣带皮层，促进痛觉敏化
Shun Hao,Man Xue,Qi-Yu Chen et al.
Shun Hao et al.
The anterior cingulate cortex (ACC) is recognized as a pivotal cortical region involved in the perception of pain. The retrosplenial cortex (RSC), located posterior to the ACC, is known to play a significant role in navigation and memory pr...
Noradrenergic inputs from the locus coeruleus to anterior piriform cortex and the olfactory bulb modulate olfactory outputs [0.03%]
蓝斑核noradrenergic神经元投射到嗅球和前梨状皮层的轴突末梢分布及其对嗅觉环路输出的调节作用
Chi Geng,Ruochen Li,Shan Li et al.
Chi Geng et al.
Norepinephrine (NE) released from locus coeruleus (LC) noradrenergic (NAergic) neurons plays a pivotal role in the regulation of olfactory behaviors. However, the precise circuits and receptor mechanisms underlying this function are not wel...
Ning Li,Hua He,Chun Xu
Ning Li
Author Correction: Unsupervised classification of brain-wide axons reveals the presubiculum neuronal projection blueprint [0.03%]
无监督分类大脑轴突揭示前旁丘脑神经元投射蓝图作者更正
Diek W Wheeler,Shaina Banduri,Sruthi Sankararaman et al.
Diek W Wheeler et al.
Published Erratum
Nature communications. 2024 Oct 28;15(1):9279. DOI:10.1038/s41467-024-53487-9 2024
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