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Ivona Viduka,Igor Štimac,Silvija Lukanović Jurić et al. Ivona Viduka et al.
Background/Objectives: Cytomegalovirus (CMV) infection expands early endosomes (EEs) into tubular extensions that may contribute to the control of virus replication and virion assembly. Sequential recruitment of protein coats and sorting ne...
Dawid S Zyla Dawid S Zyla
A combination of imaging techniques reveals how herpes simplex virus type 1 assembles within infected cells, highlighting the roles of essential viral proteins in viral assembly and exit. ...
Wei Zhang,Weiwei Li,Yang Yang et al. Wei Zhang et al.
Foot-and-mouth disease virus (FMDV) are small, icosahedral viruses that cause serious clinical symptoms in livestock. The FMDV VP1 protein is a key structural component, facilitating virus entry. Here, we find that the E3 ligase RNF5 intera...
Antoni Luque,David Reguera Antoni Luque
All matter must obey the general laws of physics and living matter is not an exception. Viruses have not only learnt how to cope with them but have managed to use them for their own survival. In this chapter, we will review some of the exci...
Carmen San Martín Carmen San Martín
Viral particles consist essentially of a proteinaceous capsid that protects the genome and is also involved in many functions during the virus life cycle. In structurally simple viruses, the capsid consists of a number of copies of the same...
Luis Valiente,Valentín Riomoros-Barahona,Juan Carlos Gil-Redondo et al. Luis Valiente et al.
Human rhinoviruses (RV) are among the most frequent human pathogens. As major causative agents of common colds they originate serious socioeconomic problems and huge expenditure every year, and they also exacerbate severe respiratory diseas...
Ankita Ray,Joshua D Simpson,Irem Demir et al. Ankita Ray et al.
Viruses represent a diverse pool of obligate parasites that infect virtually every known organism, as such, their study is incredibly valuable for a range of fields including public health, medicine, agriculture, and ecology, and the develo...
Xiaoyu Liu,Xian Xia,Michael W Martynowycz et al. Xiaoyu Liu et al.
Virus-induced cellular condensates, or viral factories, are poorly understood high-density phases where replication of many viruses occurs. Here, by cryogenic electron tomography (cryoET) of focused ion beam (FIB) milling-produced lamellae ...
Susanne Wieczorek,Jacomina Krijnse Locker Susanne Wieczorek
In this short and popular review, we summarise some of our findings analysing the replication cycles of large DNA viruses using scanning transmission electron tomography (STEM tomography) that we applied in the laboratory of Paul Walther. I...
Mandira Dutta,Kimberly A Dolan,Souad Amiar et al. Mandira Dutta et al.
M is the most abundant structural membrane protein in coronaviruses and is essential for the formation of infectious virus particles. SARS-CoV-2 M adopts two conformations, Mshort and Mlong, and regulated transition between states is hypoth...
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