Long-acting injectable cabotegravir and rilpivirine in observational cohort studies: A systematic review on virological failure, resistance and re-suppression outcomes in virally suppressed individuals living with HIV [0.03%]
长效注射卡博特格拉韦和利匹韦林在观察性队列研究中的系统评价：HIV感染者病毒学失败、耐药性和重新抑制结局的风险因素及结果
Kyle Ring,Alexa Elias,Megan Devonald et al.
Kyle Ring et al.
Introduction: Randomized controlled trial evidence suggests that long-acting injectable (LA-I) cabotegravir and rilpivirine (CAB+RPV) has similar virological failure (VF) rates to daily oral therapy, but clinical practice...
Low-level viremia linked to virological failure but not clinical events: a competing risks study [0.03%]
低水平病毒血症与病毒学失败相关但不导致临床事件：一项竞争风险研究
Enrique Bernal,Rodrigo Martínez-Rodríguez,José Miguel Gómez et al.
Enrique Bernal et al.
Introduction: The main objective of ART for people with HIV is to maintain an undetectable viral load. This study evaluates the association between low-level viremia (50-200 copies/mL) and virological failure, AIDS, and s...
Correlation between Antiretroviral Therapy Responses and Resistance to First-Line Reverse Transcriptase Inhibitors in People Living with HIV-1 Experiencing Virological Failure in South Sulawesi, Indonesia [0.03%]
印度南苏拉威西岛HIV/AIDS患者一线反转录抑制剂耐药与抗病毒治疗反应之间的相关性研究
Nurjannah -,Francisca Srioetami Tanoehardjo,Risna Halim Mubin et al.
Nurjannah - et al.
Introduction: The effectiveness of antiretroviral therapy (ART) in treating HIV is in-fluenced by the clinical response of patients, which, in turn, impacts the development of drug resistance. This study aimed to assess t...
Confirmed virological failure following enhanced adherence counseling among virally unsuppressed children and adolescents on dolutegravir-based versus other regimens: Evidence from a cohort analysis in Cameroon [0.03%]
扩大依从性咨询后接受多替拉韦基和其他方案治疗的病毒抑制失败的儿童和青少年患者：来自喀麦隆队列分析的证据
Yagai Bouba,Aude Christelle Ka&#x;e,Davy-Hyacinthe Anguechia Gouissi et al.
Yagai Bouba et al.
Achieving and maintaining viral suppression (VS) in pediatric populations remain suboptimal in low- and middle-income countries (LMICs), calling for the optimized management approaches. We compared the rate of confirmed virological failure ...
Observational Study
Medicine. 2025 May 16;104(20):e42555. DOI:10.1097/MD.0000000000042555 2025
Low-level viraemia as a risk factor for virologic failure in children and adolescents living with HIV on antiretroviral therapy in Tanzania: a multicentre, retrospective cohort study [0.03%]
坦桑尼亚接受抗逆转录病毒治疗的儿童和青少年中低水平血浆病毒载量是病毒学失败的风险因素：一项多中心回顾性队列研究
Kevin P McKenzie,Duc T Nguyen,Lilian B Komba et al.
Kevin P McKenzie et al.
Introduction: Viral load (VL) of 1000 copies/ml or greater is commonly used to define virologic failure (VF) in children and adolescents living with HIV (CALHIV) in low- and middle-income countries (LMICs). However, evide...
Multicenter Study
Journal of the International AIDS Society. 2025 May;28(5):e26474. DOI:10.1002/jia2.26474 2025
Incidence and factors associated with HIV virologic failure among adults on first-line antiretroviral therapy: A five-year retrospective study in Thailand [0.03%]
泰国初治艾滋病患者一线抗病毒治疗失败的发病率及影响因素五年的回顾性研究
Lantharita Charoenpong,Chalor Santiwarangkana,Weerawat Manosuthi
Lantharita Charoenpong
Virologic failure and HIV drug resistance have emerged with the widespread use of antiretroviral therapy (ART). Understanding these predictors is the basis for prevention strategies to achieve a high treatment success rate. A retrospective ...
Predictive factors associated with virological failure among adult patients living with HIV on first-line highly active antiretroviral therapy in Southeast Oromia, Ethiopia: a case-control study [0.03%]
埃塞俄比亚奥罗米亚南部接受一线高活性抗逆转录病毒治疗的HIV成人患者的病毒学失败相关预测因素：一项病例对照研究
Lalisa Kebebe Gedefa,Assefa Washo Bankere,Deriba Bedane et al.
Lalisa Kebebe Gedefa et al.
Objectives: The study aimed to identify the predictive factors associated with virological failure among adult patients living with HIV on first-line highly active antiretroviral therapy (HAART) in selected hospitals in S...
Virological Failure And HIV-1 Drug Resistance in Indian Adults and Adolescents on Protease Inhibitor Based Second-line Antiretroviral Therapy: A Five-year Follow-up Study [0.03%]
印度成人和青少年二线抗逆转录病毒治疗的病毒学失败及人类免疫缺陷病毒类型1耐药性的五年随访研究
Sumit Arora,Kuldeep Ashta,Nishant Raman et al.
Sumit Arora et al.
Introduction: In the changing HIV treatment landscape, the focus shifts to persons living with HIV (PLH) experiencing virological non-suppression on second-line antiretroviral therapy (ART). This includes understanding vi...
Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023 [0.03%]
东非艾滋病毒携带者在接受抗逆转录病毒治疗过程中的病毒学失败的流行率及预测因素：2016至2023年发表的研究系统评价、Meta分析和 Meta回归证据
Maria Magdalene Namaganda,Hussein Mukasa Kafeero,Joyce Nakatumba Nabende et al.
Maria Magdalene Namaganda et al.
Background: Virological failure (VF) significantly threatens the efficacy of antiretroviral therapy (ART) programs in East Africa. This systematic review and meta-analysis assess the prevalence and predictors of VF among ...
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