Omic Risk Scores are Associated with COPD-related Traits Across Three Cohorts [0.03%]
三个队列中 omic 风险评分与慢性阻塞性肺疾病特征相关性研究
Iain R Konigsberg,Luciana B Vargas,Katherine A Pratte et al.
Iain R Konigsberg et al.
Background: Chronic obstructive pulmonary disease (COPD) exhibits marked heterogeneity in lung function decline, mortality, exacerbations, and other disease-related outcomes. Omic risk scores (ORS) estimate the cumulative...
Comprehensive evaluation of disease characteristics and outcomes of patients with extramedullary multiple myeloma in the modern era [0.03%]
现代多发性骨髓瘤患者病灶性疾病特征及转归的全面评估研究
Megan Broughton,Subodh Bhatta,Doshi Sonali et al.
Megan Broughton et al.
Multiple myeloma (MM) derives from the clonal proliferation of plasma cells, primarily residing in the bone marrow. However, MM cells can disseminate systemically, leading to osseous or soft tissue extramedullary disease (EMM) or plasma cel...
Identification of a presymptomatic and early disease signature for Amyotrophic Lateral Sclerosis (ALS): protocol of the premodiALS study [0.03%]
无症状期和肌萎缩侧索硬化症（ALS）早期疾病特征的识别：premodiALS研究方案
Laura Tzeplaeff,Ana Galhoz,Clara Meijs et al.
Laura Tzeplaeff et al.
The median time to diagnosis of amyotrophic lateral sclerosis (ALS) is approximately 12 months after the onset of first symptoms. This diagnostic delay is primarily due to the nonspecific nature of early symptoms and the clinical challenges...
Population-Based Big Data Analysis on Disease Patterns in Patients Identified With Juvenile Idiopathic Arthritis Using National Claims Data [0.03%]
基于人口的大型数据分析国家理赔数据中诊断为幼年特发性关节炎患者的疾病特征
Eun Jeong Min,Soo Hyun Lee,Joo-Young Jo et al.
Eun Jeong Min et al.
Background: This study aimed to identify epidemiologic data, including prevalence and incidence, of patients with juvenile idiopathic arthritis (JIA) in accordance with the diseases diagnostic code and Rare Intractable Di...
A Landmark Multiyear Study of Alzheimer Disease: Integrating [18F]FEPPA PET Imaging With 12 Clinical Assessments for Comprehensive Disease Profiling [0.03%]
阿尔茨海默病的一项里程碑式的多年度研究：整合[18F]FEPPA-PET成像和12种临床评估以实现全面的疾病特征分析
Skye Hsin-Hsien Yeh,Yung-Shuan Lin,Wei-Ju Lee et al.
Skye Hsin-Hsien Yeh et al.
Purpose: This multiyear study aimed to investigate the relationship between TSPO expression and cognitive decline in Alzheimer disease (AD) using [18F]FEPPA PET imaging. We integrated this imaging data with 12 comprehensi...
Characterization of Secondary Health Conditions Among United States Service Members with Combat-Related Lower Extremity Limb Salvage [0.03%]
美国现役军人作战相关下肢保肢的继发性疾病特征分析
Sarah R Franco,Susan L Eskridge,Stephen M Goldman et al.
Sarah R Franco et al.
Background: Musculoskeletal trauma involving the lower extremities is an unfortunately prevalent injury pattern in contemporary warfare, and the secondary health conditions (SHCs) associated with these injuries remain largely unexplored. Me...
Disease characteristics and monitoring of IDH1/IDH2-mutated acute myeloid leukemia [0.03%]
IDH1/IDH2突变急性髓系白血病的临床特征及监测指标分析
Mélinda Dantec,Maxime Dufossé,Augustin Boudry et al.
Mélinda Dantec et al.
Robina K Coker,Kathy M Cullen
Robina K Coker
Sarcoidosis is a complex disease of unknown origin, primarily affecting the lungs but capable of involving almost any organ. Diagnosis is challenging due to the lack of specific markers and requires assessment of clinical features, careful ...
Corrigendum to ''Disease characteristics, treatments, and outcomes of patients with pulmonary arterial hypertension treated with selexipag in real-world settings from the SPHERE registry (SelexiPag: tHe usErs dRug rEgistry)'' [J Heart Lung Transplant 43 (2024) 272-283] [0.03%]
对“SPHERE登记处接受塞利西帕格治疗的肺动脉高压患者的疾病特征、治疗和结局”[J Heart Lung Transplant 43 (2024) 272-283]的勘误表
Vallerie McLaughlin,Harrison W Farber,Kristin B Highland et al.
Vallerie McLaughlin et al.
Real-world characteristics & disease history of patients with X-linked hypophosphatemia before treatment with burosumab [0.03%]
接受布罗舒马治疗前慢性X连锁维生素D抵抗性佝偻病/低磷血症患者的疾病特征及临床表现
Kathryn M Dahir,Zhiyi Li,Heather M Heerssen et al.
Kathryn M Dahir et al.
In a United States claims database, 1,358 persons with familial hypophosphatemia who began treatment with burosumab were identified. Prior to treatment, high rates of several morbidities were coded including osteoarthritis, fractures, enthe...
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