Gut-brain-liver axis in growth hormone deficiency: role of microbiota-derived short-chain fatty acids in ethnic variability and therapeutic development [0.03%]
生长激素缺乏症中的肠-脑-肝轴：肠道菌群衍生的短链脂肪酸在种族差异和药物开发中的作用
Dongming Meng,Wei Kong,Sai Cheng et al.
Dongming Meng et al.
Growth hormone deficiency (GHD) is a pediatric endocrine disorder characterized by dysregulated growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis activity and gut microbiota imbalance. Emerging evidence highlights the gut-brain-li...
Diagnosis of growth hormone deficiency: searching for Consensus along life [0.03%]
生长激素缺乏症的诊断：一生之中寻求共识
Flavia Prodam,Pietro Maffei
Flavia Prodam
An Update on Reducing Adverse Events Associated With the Glucagon Stimulation Test for the Assessment of Growth Hormone Deficiency in Adults [0.03%]
关于降低葡萄糖刺激试验相关不良事件以评估成人生长激素缺乏的最新研究进展
Philippa Trevella,Carmela Caputo,Caroline Jung et al.
Philippa Trevella et al.
Research progress in abnormal carbohydrate, lipid, and protein metabolism in children with isolated growth hormone deficiency [0.03%]
孤立性生长激素缺乏症儿童异常糖脂蛋白代谢的研究进展
Tingting Zhao,Yan Ma,Zhimin Zheng et al.
Tingting Zhao et al.
Introduction: Growth hormone deficiency (GHD) is a rare endocrine disorder characterized by reduced or insufficient secretion of growth hormone (GH). GHD manifests with a heterogenous spectrum of symptoms mainly affecting...
Spontaneous postpartum recovery of mild traumatic brain injury induced growth hormone deficiency [0.03%]
产后自发恢复轻度创伤性脑损伤引起的生长激素缺乏症
Jason B Tabor,Kirstie Lithgow,Gregory A Kline et al.
Jason B Tabor et al.
A woman in her late 20s developed persistent post-concussion symptoms (PPCS) following a mild traumatic brain injury (mTBI) sustained in a motor vehicle collision. Symptoms included daily headaches, cognitive and physical fatigue and vision...
Case Reports
BMJ case reports. 2025 Jun 2;18(6):e264400. DOI:10.1136/bcr-2024-264400 2025
Comparative Efficacy of Once-Weekly Somatrogon Versus Daily Growth Hormone Therapy in Children With Idiopathic Growth Hormone Deficiency: A Real-World Retrospective Study From Greece [0.03%]
希腊真实世界回顾性研究： idiopathic生长激素缺乏儿童一周一次somatrogon与每日生长激素治疗的疗效比较
Sokratis Katsoudas,Evangelia Tsitsekli,Ioannis Pichlinski et al.
Sokratis Katsoudas et al.
Introduction Short stature is one of the most common reasons for referral to a pediatric endocrinologist, defined as a height of at least two standard deviations (SD) below the mean for age and sex. In this study, we aimed to compare the ef...
Efficacy and Safety of Three-Years Growth Hormone Treatment in Girls With Turner Syndrome and Growth Hormone Deficiency: A Case-Control Study [0.03%]
三年生长激素治疗Turner综合征伴生长激素缺乏症的女孩的疗效和安全性：病例对照研究
Rosario Ferrigno,Daniela Cioffi,Valeria Pellino et al.
Rosario Ferrigno et al.
Background: Turner syndrome (TS) is a chromosomal disorder characterized by specific clinical features, including cardiac and renal malformations and short stature. In these patients, recombinant growth hormone (GH) treat...
Efficacy, safety, and insulin-like growth factor I of weekly somapacitan in children with growth hormone deficiency: 3-year results from REAL4 [0.03%]
REAL4研究：长效somapacitan治疗儿童生长激素缺乏症的疗效、安全性和胰岛素样生长因子-I水平：为期3年的结果
Bradley S Miller,Joanne C Blair,Michael Højby Rasmussen et al.
Bradley S Miller et al.
Objective: Somapacitan is a long-acting GH approved for once-weekly treatment of GH deficiency (GHD). This study aims to evaluate the efficacy and tolerability of somapacitan after 3 years of treatment and 2 years after s...
Disrupted small-world networks in children with drug-naïve growth hormone deficiency: a DTI-based network analysis [0.03%]
基于弥散张量成像的网络分析在未经治疗的生长激素缺乏儿童中发现小世界模型受损
Yasen Alimire,Yanglei Cheng,Huaqiong Qiu et al.
Yasen Alimire et al.
Background: Growth hormone deficiency (GHD) in children results from impairment of the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis. Although GHD's effects on brain structure and function have been studied,...
Functional study of two siblings with isolated growth hormone deficiency and pituitary MR imaging abnormalities caused by a novel HESX1 variant [0.03%]
功能研究与垂体MRI异常表现的新基因HESX1变异所致孤立性生长激素缺乏症两兄弟病例报告
NokI Lei,Yun Yang,Yanlin Liu et al.
NokI Lei et al.
Purpose: Our study identifies a novel HESX1 variant in two siblings, resulting in isolated growth hormone deficiency (IGHD) associated with empty sella. To the best of our knowledge, this represents the second recognized ...
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