Enhancing the Diagnostic Yield of EGD for Diagnosis of Barrett Esophagus Through Methylated DNA Biomarker Triage [0.03%]
通过甲基化DNA生物标志物筛选提高内镜诊断巴雷特食管的阳性率
Jayde E Kurland,Sheena B Patel,Richard Englehardt et al.
Jayde E Kurland et al.
Background: EsoGuard (EG) is a methylated DNA assay for cells collected nonendoscopically with EsoCheck for detection of Barrett esophagus (BE) and can be utilized as a triage to esophagogastroduodenoscopy (EGD) in patien...
Profiling 92 circulating neurobiological proteins identifies novel candidate biomarkers of long-term cognitive outcome after ischemic stroke [0.03%]
缺血性脑卒中患者血清神经生物学蛋白候选生物标志物筛选及验证研究
Cecilia Lagging,Annie Pedersen,Max Petzold et al.
Cecilia Lagging et al.
The biological underpinnings of post-stroke cognitive function are largely unknown, and protein investigations can point towards important pathways for further study. We profiled plasma levels of 91 neurology-related proteins (Olink Neurolo...
Evaluation of urinary metabolites as biomarkers for occupational p-chloronitrobenzene exposure: a pilot study [0.03%]
Occupational p-氯硝基苯暴露的尿代谢产物生物标志物筛选研究
Peng Wang,Lifang Han,Hua Zou et al.
Peng Wang et al.
We explored the feasibility of using urinary metabolites of p-chloronitrobenzene (p-CNB) as exposure biomarkers of occupational p-CNB exposure. Forty-two workers exposed to p-CNB during their jobs at a chemical enterprise in Shaoxing, Zheji...
A deep learning framework for enhanced mass spectrometry data analysis and biomarker screening [0.03%]
一种用于增强质谱数据评估和生物标志物筛查的深度学习框架
Shuyu Zhang,Zhiyu Li,Weili Peng et al.
Shuyu Zhang et al.
Mass spectrometry (MS) serves as a powerful analytical technique in metabolomics. Traditional MS analysis workflows are heavily reliant on operator experience and are prone to be influenced by complex, high-dimensional MS data. This study i...
Serum Disease-specific IgG Fc Glycosylation as Potential Biomarkers for Nonproliferative and Proliferative Diabetic Retinopathy Using Mass Spectrometry [0.03%]
基于质谱分析的糖尿病视网膜病变血清病灶特异性IgG Fc岩藻糖基化糖链生物标志物筛选研究
Yishuang Mao,Jiyun Zhang,Yixin Zhang et al.
Yishuang Mao et al.
Purpose: To investigate the potential of serum disease-specific immunoglobulin G (DSIgG) crystallizable fragment (Fc) N-glycosylation as a diagnostic biomarker for the identification of nonproliferative and proliferative ...
Aroma analysis and biomarker screening of 27 tea cultivars based on four leaf color types [0.03%]
基于4种叶色类型对27个茶树品种的香气分析及风味物质筛选
Feiquan Wang,Hua Feng,Yucheng Zheng et al.
Feiquan Wang et al.
Green is no longer the only color used to describe tea leaves. As tea plants with different leaf colors-white, yellow, and purple-yield significant economic benefits, scholars are growing increasingly curious about whether these differently...
Screening of obstructive sleep apnea and diabetes mellitus -related biomarkers based on integrated bioinformatics analysis and machine learning [0.03%]
基于综合生物信息学分析和机器学习的阻塞性睡眠呼吸暂停与糖尿病相关生物标志物筛选研究
Jianan Yang,Yujie Han,Xianping Diao et al.
Jianan Yang et al.
Background: The pathophysiology of obstructive sleep apnea (OSA) and diabetes mellitus (DM) is still unknown, despite clinical reports linking the two conditions. After investigating potential roles for DM-related genes i...
Research on Prediction of Multiple Degenerative Diseases and Biomarker Screening Based on DNA Methylation [0.03%]
基于DNA甲基化的多重退行性疾病预测及生物标志物筛选研究
Ruoting Tian,Hao Zhang,Chencai Wang et al.
Ruoting Tian et al.
The aging process will lead to a gradual functional decline in the human body, and even accelerate a significantly increased risk of degenerative diseases. DNA methylation patterns change markedly with one's age, serving as a biomarker of b...
Screening of serum biomarkers in patients with PCOS through lipid omics and ensemble machine learning [0.03%]
基于脂质组学和集成机器学习的多囊卵巢综合征患者血清生物标志物筛选研究
Ji-Ying Chen,Wu-Jie Chen,Zhi-Ying Zhu et al.
Ji-Ying Chen et al.
Polycystic ovary syndrome (PCOS) is a primary endocrine disorder affecting premenopausal women involving metabolic dysregulation. We aimed to screen serum biomarkers in PCOS patients using untargeted lipidomics and ensemble machine learning...
Unveiling the role of lipopolysaccharide-related genes in diabetic retinopathy: identification of key biomarkers and immune infiltration analysis [0.03%]
糖尿病视网膜病变中脂多糖相关基因的作用机制及关键生物标志物筛选和免疫浸润分析研究
Hongyi Sun,Shaohua Liu,Chao Wei
Hongyi Sun
Background: Growing evidence suggests a link between systemic lipopolysaccharide (LPS) exposure and worsening diabetic retinopathy (DR). This study aims to investigate DR's pathogenesis by analyzing LPS-related genes (LRG...
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