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Makoto Niwa,Kenta Noda,Yoshiyuki Kobayashi et al. Makoto Niwa et al.
Purpose: Using two diseases, Alzheimer's disease and muscular dystrophy as examples, in which many resources have been invested, trends in bioanalytical techniques for detection of peptide or protein biomarkers using mass...
Mari Aksnes Mari Aksnes
Background: Alzheimer's disease (AD), the most common cause of dementia, affects twice as many women as men. Moreover, sex is increasingly recognised as an important factor for AD, influencing symptom presentation, progre...
Alessia Vignoli,Gianmaria Miolo,Leonardo Tenori et al. Alessia Vignoli et al.
Soft tissue sarcomas (STSs) are rare malignant tumors that are difficult to prognosticate using currently available instruments. Omics sciences could provide more accurate and individualized survival predictions for patients with metastatic...
Noémie Reynaud,Laura Belz,David Béal et al. Noémie Reynaud et al.
UV-induced formation of photoproducts in DNA is a major initiating event of skin cancer. Consequently, many analytical tools have been developed for their quantification in DNA. In the present work, we extended our previous liquid chromatog...
Alexander G Thompson,Elizabeth Gray,Nick Verber et al. Alexander G Thompson et al.
The routine clinical integration of individualized objective markers of disease activity in those diagnosed with the neurodegenerative disorder amyotrophic lateral sclerosis is a key requirement for therapeutic development. A large, multice...
Henrik Zetterberg Henrik Zetterberg
The past few years have seen an explosion in sensitive and specific assays for cerebrospinal fluid (CSF) and blood biomarkers for Alzheimer's disease (AD) and related disorders, as well as some novel assays based on pathological seed-induce...
Sultan Aitekenov,Alisher Sultangaziyev,Perizat Abdirova et al. Sultan Aitekenov et al.
This review surveys Infrared, Raman/SERS and Brillouin spectroscopies for medical diagnostics and detection of biomarkers in biofluids, that include urine, blood, saliva and other biofluids. These optical sensing techniques are non-contact,...
Becky C Carlyle,Bianca A Trombetta,Steven E Arnold Becky C Carlyle
Neurodegenerative dementias are highly complex disorders driven by vicious cycles of intersecting pathophysiologies. While most can be definitively diagnosed by the presence of disease-specific pathology in the brain at postmortem examinati...
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