Effect of compound glycyrrhizin combined with fractional CO2 laser on the improvement of skin lesions and skin barrier function in rosacea [0.03%]
甘草酸二铵联合点阵二氧化碳激光治疗改善玫瑰痤疮皮肤屏障及皮损疗效观察
Si-Cheng Zhao,Dan Wang,Ting-Yan Wu et al.
Si-Cheng Zhao et al.
Rosacea is a chronic facial inflammatory disease affecting quality of life, with complex causes including psychological, lifestyle and immune factors. This study examines the use of compound glycyrrhizin with fractional CO2 laser treatment ...
Randomized Controlled Trial
Pakistan journal of pharmaceutical sciences. 2025 Mar-Apr;38(2):407-411. DOI: 2025
Glycyrrhizic acid mitigates hepatocyte steatosis and inflammation through ACE2 stabilization via dual modulation of AMPK activation and MDM2 inhibition [0.03%]
甘草酸通过AMPK活化和MDM2抑制的双向调节稳定ACE2从而缓解肝细胞脂肪变性和炎症反应
Longyue Zhou,Yun Yi,Bingqi Lin et al.
Longyue Zhou et al.
As a hepatoprotective phytochemical derived from Glycyrrhiza species, glycyrrhizic acid (GA) exhibits unique dual-target therapeutic efficacy against metabolic-driven hepatic steatosis and inflammation. Building upon our previous finding th...
High plasma 18β-glycyrrhetinic acid levels are associated with more intensive antihypertensive treatment, resistant hypertension and apparent mineralocorticoid excess in patients with type 2 diabetes [0.03%]
血浆18β-甘草酸水平与2型糖尿病患者的抗高血压治疗强度、难治性高血压及假性盐皮质激素增多症有关
Jakob L Wetche,Anne V Schmedes,Amalie Sjøgren et al.
Jakob L Wetche et al.
Background: Excessive consumption of glycyrrhizin, a licorice-derived substance, can cause blood pressure (BP) elevation and apparent mineralocorticoid excess (AME). However, self-reported intake can be unreliable due to ...
Engineered celastrol liposomes with glycyrrhizic acid augment synergistic antitumor efficacy in breast cancer [0.03%]
甘草酸工程化雷公藤内酯脂质体在乳腺癌中的协同抗肿瘤研究
Wei Zhang,Jiping Li,Xiuli Gao et al.
Wei Zhang et al.
Background/objectives: Breast cancer treatment remains challenged by the non-specific distribution and systemic toxicity of conventional chemotherapeutics. Celastrol (CEL), a natural compound with antitumor efficacy, face...
Glycyrrhetinic acid and RGD dual-targeted liposomes for combined chemotherapy and phototherapy in liver cancer [0.03%]
甘草酸和RGD双靶向脂质体在肝癌化光联合治疗中的应用研究
Qian Zhang,Xiaohui Tang,Xiangyun Xie et al.
Qian Zhang et al.
This study aims to develop a multifunctional nanodelivery system for the precise treatment of liver cancer. The treatment of liver cancer faces challenges such as low drug delivery efficiency and strong drug resistance, especially in the co...
18β-Glycyrrhetinic acid from Glycyrrhiza Uralensis protects colonic epithelium in ulcerative colitis by activating Wnt/β-catenin pathway to restore tight junction [0.03%]
甘草酸通过激活Wnt/β-catenin信号通路修复紧密连接来保护溃疡性结肠炎的结肠上皮细胞
Xi Peng,Rao Zhong,Shi Dong et al.
Xi Peng et al.
Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by persistent inflammation of the colon. Glycyrrhiza uralensis extract (ULE), a traditional medicinal plant extract, is globally re...
Transcriptome and Metabolomics Analysis Reveal the Effects of Red and Blue Light on the Physiology and Primary Medicinal Components (Liquiritin and Glycyrrhizic Acid) of Glycyrrhiza uralensis Seedlings [0.03%]
转录组和代谢组分析揭示了红蓝光对甘草幼苗生理及主要药用成分（甘草素和甘草酸）的影响
Yuan Jiang,Zhengru Zhang,Shurui Zhang et al.
Yuan Jiang et al.
Glycyrrhiza uralensis Fisch. is considered one of the most economically important medicinal plants worldwide. However, the quality of cultivated G. uralensis has not been adequate to meet the market demand. As one of the most important fact...
Successful Treatment with a Combination of Oral and Topical Glycyrrhizinic Acid in an Immunocompetent Anogenital Warts Patient [0.03%]
免疫功能正常的生殖器尖锐湿疣患者的甘草酸联合口服和外用药治疗成功案例
Pati Aji Achdiat,Safira Mitayani Pranata,Retno Hesty Maharani
Pati Aji Achdiat
Introduction: Anogenital warts (AGW) are benign proliferative diseases caused by human papillomaviruses (HPV), characterized by verrucous papules on the genital or anal region In line with these findings, the prevalence o...
Glycyrrhizic Acid Ameliorates Sepsis-Induced Acute Lung Injury Through Suppression of Endoplasmic Reticulum Stress [0.03%]
甘草酸通过抑制内质网应激改善脓毒症诱导的急性肺损伤
Ling Fang,Xuepan Wang,Wei Guan
Ling Fang
Background: Sepsis-mediated acute lung injury (ALI) has a high mortality rate, and glycyrrhizic acid (GA) possesses diverse pharmacologic activities. Herein, we investigated the role of GA in attenuating sepsis-triggered ...
Overwhelming glycyrrhizin production in Glycyrrhiza glabra induced by rihizobial symbiosis [0.03%]
根瘤菌共生诱导的甘草酸生产研究
Shion Yamamoto,Aya Shimomura,Satoshi Watanabe et al.
Shion Yamamoto et al.
We reported that Glycyrrhiza uralensis inoculated with rhizobium tended to increase biomass production and glycyrrhizic acid (GL) production, in this study we have also achieved drastically increase in biomass and GL production in Glycyrrhi...
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