inCu-click: DNA-enhanced ligand enables live-cell, intracellular click chemistry reaction with copper catalyst [0.03%]
活细胞内含铜催化剂的点击化学反应：一种增强型配体诱导铜分子活性参与反应(inCu-click：DNA增强配体使铜催化活细胞内的点击化学反应)
Keqing Nian,Yifang Liu,Yuchen Qiu et al.
Keqing Nian et al.
Labeling cellular biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) offers rapid reaction kinetics and uses small azide and alkyne probes that minimally disturb molecular function, making it ideal for tracking biomolecule...
Christopher M Butch,Patrick C Hillesheim,Arsalan Mirjafari
Christopher M Butch
In this Comment, we suggest salt metathesis (or ion exchange) as an ultimate click reaction, extending click chemistry principles beyond covalent bonds to ionic interactions. These universal and robust reactions, which nature utilizes in ma...
A new thiol-sulfur click chemistry for lithium-organosulfide batteries [0.03%]
锂有机硫电池的一种新型巯基-硫点击化学反应
Rong Zou,Wenwu Liu,Fen Ran
Rong Zou
Click chemistry is a rapid, reliable, and powerful function and a highly selective organic reaction that facilitates the efficient synthesis of various molecules by joining small units. This approach has found widespread applications in fie...
Flavanone-Enabled CuAAC Reaction: Noninnocent Reagents Driving a Mononuclear Mechanism Over the Dinuclear Paradigm [0.03%]
黄酮酮启用的CuAAC反应：非惰性试剂推动单核机制超越双核范式理论
Eloah Pereira Ávila,Larissa A de Oliveira,Brenno A D Neto et al.
Eloah Pereira Ávila et al.
In this work, we report the use of the CuAAC (copper-catalyzed azide-alkyne cycloaddition) reaction to obtain different triazole derivatives bridged to the naringenin skeleton, leading to the combination of a triazole pharmacophoric group w...
The inverse electron demand diels-alder (IEDDA): A facile bioorthogonal click reaction for development of injectable polysaccharide-based hydrogels for biomedical applications [0.03%]
反向电子需求狄尔斯-阿尔德反应（IEDDA）：一种用于开发适用于生物医学应用的可注射多糖基水凝胶的便利生物正交点击反应
Linying Yan,Zhenzhen Zhao,Yuqian Liu et al.
Linying Yan et al.
The inverse electron demand Diels-Alder (IEDDA) cycloaddition between tetrazines and strained dienophiles is recognized as a fast and specific reaction. The integrating tetrazines and strained dienophiles onto the backbone of polysaccharide...
The Network Construction of a New Byproduct-Free XLPE-Based Insulation Using a Click Chemistry-Type Reaction and a Theoretical Study of the Reaction Mechanism [0.03%]
一种新型不含副产物的XLPE绝缘材料的点击化学型网络构建及反应机理的理论研究
Yang Du,Hui Zhang,Wei Han et al.
Yang Du et al.
Cross-linked polyethylene (XLPE) is applied in most advanced high-voltage direct-current (HVDC) power cable insulations, which are produced via dicumyl peroxide (DCP) technology. The electrical conductivity of insulation material can be inc...
Jiantao Zhao,Huacheng Yu,Xingchen Jin et al.
Jiantao Zhao et al.
Click reactions, which are characterized by rapid, high-yielding, and highly selective coupling of two reaction partners, are powerful tools in synthesis but are rarely reversible. Innovative strategies that reverse such couplings in a prec...
Development of Alginate-Based Biodegradable Radioactive Microspheres Labeled with Positron Emitter through Click Chemistry Reaction: Stability and PET Imaging Study [0.03%]
通过点击化学反应开发基于海藻酸盐的可生物降解放射性微球及其稳定性及PET成像研究
Arun Gupta,Ji Yong Park,Hyunjun Choi et al.
Arun Gupta et al.
Biodegradable radioactive microspheres labeled with positron emitters hold significant promise for diagnostic and therapeutic applications in cancers and other diseases, including arthritis. The alginate-based polymeric microspheres offer a...
Photo-Clickable Triazine-Trione Thermosets as Promising 3D Scaffolds for Tissue Engineering Applications [0.03%]
用于组织工程应用的具有点击化学反应性的光交联三嗪-三酮热固性材料作为有前景的3D支架
Åshild Johansen,Jinjian Lin,Shuntaro Yamada et al.
Åshild Johansen et al.
There is an overwhelming demand for new scaffolding materials for tissue engineering (TE) purposes. Polymeric scaffolds have been explored as TE materials; however, their high glass transition state (Tg) limits their applicability. In this ...
An LF-NMR homogeneous sensor for highly sensitive and precise detection of E. coli based on target-triggered CuAAC click reaction [0.03%]
一种基于目标触发CuAAC“点击化学反应”的高灵敏度和高精度检测E. coli的LF-NMR同相传感器
Fan Yang,Le Chen,Huiqian Zhou et al.
Fan Yang et al.
In this study, a low field nuclear magnetic resonance (LF-NMR) homogeneous sensor was constructed for detection of Escherichia coli (E. coli) based on the copper metabolism of E. coli triggered click reaction. When live E. coli was present,...
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