Biomimetic Targeted Nanoplatform Exerts a Combined Effect of Alleviating Calcium Overload and Scavenging ROS to Attenuate the Inflammatory Response in Myocardial Ischemia-Reperfusion Injury [0.03%]
仿生靶向纳米平台通过联合减轻钙超载和清除ROS作用来缓解心肌缺血再灌注损伤炎症反应
Lin Liu,Shimiao Wu,Jingya Xiu et al.
Lin Liu et al.
The myocardial ischemia-reperfusion injury (MIRI) is an acute and serious disease with complex pathogenesis, which is intricately associated with oxidative stress, calcium overload, and inflammation. Currently, widely utilized antioxidant o...
The OsAP4-OsCATA/OsCATC Regulatory Module Orchestrates Drought Stress Adaptation in Rice Seedlings Through ROS Scavenging [0.03%]
OsAP4-OsCATA/OsCATC调控模块通过清除ROS协调水稻幼苗的干旱胁迫适应性
Yifei Jiang,Bin Xie,Xiong Luo et al.
Yifei Jiang et al.
Drought stress poses a major constraint on global crop productivity. Although aspartic proteases (APs) are primarily characterized in plant disease resistance, their roles in abiotic stress adaptation remain largely unexplored. Here, we dem...
Gelatin/hyaluronic acid-based in situ forming hydrogel promotes wound regeneration by the synergy of ROS-scavenging and pro-healing activity [0.03%]
基于明胶/透明质酸的原位形成水凝胶通过协同清除ROS和促愈合作用促进伤口再生
Xingchen Zhao,Wenling Dai,Chenxin Liu et al.
Xingchen Zhao et al.
The development of advanced hydrogel dressings that integrate biocompatibility, antioxidant activity and dynamic adaptability remains critical for addressing the complex demands of modern wound management. In this study, we designed a multi...
Novel nanocomposites eliminate excess macrophage extracellular traps for anti-inflammatory therapy by scavenging ROS and inducing macrophages polarizing to M2 type [0.03%]
新型纳米复合材料通过清除ROS并诱导巨噬细胞极化为M2型来消除过多的中性粒细胞胞外诱捕网以进行抗炎治疗
Ke Wang,Xiaomin Xia,Nan Wang et al.
Ke Wang et al.
Macrophage extracellular traps (METs) are protein network structures released by macrophages during immune defense initiation and inflammation regulation. Evidence shows that these protein structures can help kill pathogens. However, overpr...
Engineered Probiotics for Colitis Therapy by Improving Intestinal Colonization and Scavenging ROS [0.03%]
通过提高肠道定植和清除ROS治疗结肠炎的工程益生菌
Siyuan Yuan,Xiaomei Dai,Yuqin Zou et al.
Siyuan Yuan et al.
Probiotics hold significant promise for treating colitis, but their application remains challenging because of insufficient colonization and survival against colorectal oxidative stress. Herein, engineered probiotics were prepared to enhanc...
Resveratrol-loaded engineered microcapsules with dual antimicrobial and ROS-scavenging for programmed wound healing [0.03%]
用于程序性伤口愈合的负载白藜芦醇工程微胶囊其具有双重抗菌和清除ROS功能
Anning Wang,Xiang Lin,Xirui Wang et al.
Anning Wang et al.
Hydrogel microparticles have been proved effective for the skin wound repair. Attempts in this area focus on how to enrich the structures and encapsulate bioactive substances to achieve the spatially controllable release for accelerated wou...
PEG-Coated Ceria-Zirconia Nanoparticle Prevent Weight Gain and Obesity-Related Organ Damage Through Autophagy Flux Activation and ROS Scavenging [0.03%]
PEG修饰的氧化铈-氧化锆纳米粒子通过激活自噬流和清除ROS防止体重增加及肥胖相关器官损伤
Eun Kyung Kim,Sang-Eun Hong,Yun Seok Choi et al.
Eun Kyung Kim et al.
Purpose: Obesity is becoming a global health problem that leads to serious complications. Despite numerous efforts to lose weight, achieving this goal is very difficult. Polyethylene glycol-coated ceria-zirconia nanoparti...
The Transcription Factor LpWRKY65 Enhances Embryogenic Capacity through ROS Scavenging during Somatic Embryogenesis of Larch [0.03%]
油松体胚发生过程中转录因子LpWRKY65通过清除ROS提高合子胚的胚状体发生能力
Xiaoyi Chen,Luyao Zhang,Chengbi Liu et al.
Xiaoyi Chen et al.
Somatic embryogenesis is a powerful system for studying embryo development and scaling up the production of elite genetic material. Somatic embryogenesis has been well established in Larix principis-rupprechtii, a Chinese larch species domi...
NIPAAm-co-PEG4000 thermoresponsive hydrogel with ROS scavenging properties improves in vivo border zone contractility and reduces myocardial remodeling in sheep after MI [0.03%]
具有ROS清除性能的NIPAAm-co-PEG4000温敏水凝胶改善绵羊心梗后心肌边界区收缩功能并减少不良重塑
Vicky Y Wang,Yang Zhu,Kimberly A Spaulding et al.
Vicky Y Wang et al.
Decreased contractility of the border zone (BZ) myocardium after MI is associated with oxidative stress mediated contractile protein dysfunction. We hypothesized that injection of a thermo-responsive hydrogel with enhanced reactive oxygen s...
A NIR-II Laser-Triggered Nb2C-Arg/Gel Composite Multifunctional Hydrogel with Photothermal, ROS Scavenging, and NO Release for Infected Wound Healing [0.03%]
一种NIR-II激光触发的Nb2C-arg/凝胶复合多功能水凝胶用于感染伤口修复，具有光热、ROS清除和NO释放功能
Mi Liu,Weidan Zhao,Denghao Li et al.
Mi Liu et al.
Infected wound healing remains a significant clinical challenge due to bacterial resistance and excessive inflammation. Herein, a multifunctional hydrogel dressing (Nb2C-Arg/Gel) is developed that integrates two-dimensional Nb2C nanosheets ...
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