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Prabhavathi Sundaram,Sathish Sundar Dhilip Kumar,Heidi Abrahamse Prabhavathi Sundaram
Background: Globally, colorectal cancer (CRC) is the third-most diagnosed cancer among males and the second-most diagnosed cancer among females. In cancer, stem cells are a subset of neoplastic cells capable of tumorigenesis and exhibit pro...
Lijun Su,Yixi Zhu,Xuebo Li et al. Lijun Su et al.
Recently, photodynamic therapy (PDT) has gained considerable attention as a promising therapeutic approach for the treatment of psoriasis. Unfortunately, the activation of high mobility group box 1 protein (HMGB1) by PDT triggers innate and...
Anna Kruczek-Kazibudzka,Barbara Lipka,Jakub Fiegler-Rudol et al. Anna Kruczek-Kazibudzka et al.
Oral potentially malignant disorders (OPMDs) are conditions that carry an increased risk of malignant transformation, including oral leukoplakia and oral lichen planus. Current management approaches differ based on each condition's unique e...
A V Ryabova,I D Romanishkin,I V Markova et al. A V Ryabova et al.
The application of photosensitizers for inhibition of oxidative phosphorylation in order to temporally decrease oxygen uptake by tumor cells in the course of photodynamic therapy (PDT) evokes growing interest. The aim of the study is to ove...
Manuele Di Sante,Alena Kaltenbrunner,Marco Lombardo et al. Manuele Di Sante et al.
Chlorin e6 (Ce6) and fullerene (C60) are among the most used photosensitizers (PSs) for photodynamic therapy (PDT). Through the combination of the chemical and photophysical properties of Ce6 and C60, in principle, we can obtain an "ideal" ...
Fei Huang,Yu Li,Xing-Jie Zhang et al. Fei Huang et al.
Since tyrosine kinase inhibitor (TKI) could reverse ABCG2-mediated drug-resistance, novel chlorin e6-based conjugates of Dasatinib and Imatinib as photosensitizer (PS) were designed and synthesized. The results demonstrated that conjugate 1...
Til Bahadur Thapa Magar,Shyam Kumar Mallik,Pallavi Gurung et al. Til Bahadur Thapa Magar et al.
Skin photoaging due to ultraviolet B (UVB) exposure generates reactive oxygen species (ROS) that increase matrix metalloproteinase (MMP). Chlorin e6-photodynamic therapy (Ce6-PDT), in addition to being the first-line treatment for malignanc...
Hongqing Yao,Jian-Ying Zhou Hongqing Yao
Introduction: The effective treatment of glioblastoma still remains a great challenge. We herein report the development of chlorin e6 (Ce6)-conjugated iron oxide (Fe3O4-Ce6) nanoparticles for ablation of glioblastoma cells via combining pho...
Gabriel Garcia de Carvalho,Patricia Milagros Maquera-Huacho,Cristiano Silva Pontes et al. Gabriel Garcia de Carvalho et al.
In our previous studies, Chlorin-e6 (Ce6) demonstrated a significant reduction of microorganisms' viability against multi-species biofilm related to periodontitis while irradiated with blue light. However, the conjugation of Ce6 and antimic...
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