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Markus Roessler,Sarah Anja Müller,Andreas Schaper Markus Roessler
Background: Cases of poisoning account for 3-7% of all emergency medical services (EMS) calls. At present it is not known which toxins are responsible for severe and fatal poisoning in Germany. ...
Eléonore Bouchereau,Estelle Pruvost-Robieux,Shidasp Siami et al. Eléonore Bouchereau et al.
Background and objectives: Absent cough reflex is associated with mortality in intensive care unit (ICU) patients requiring deep sedation, suggesting that lower brainstem dysfunction contributes to adverse outcomes. We co...
Shuyin Li,Jason W Shapiro,Hardik Shah et al. Shuyin Li et al.
Immune checkpoint blockade therapies have transformed the landscape of cancer care, but durable clinical responses are achieved in only a subset of patients. To identify genes that can contribute to immunotherapy resistance, a genome-wide C...
Patricia D B Tiburcio,Kavita Desai,Austin Warne et al. Patricia D B Tiburcio et al.
Background: Inhibition of immune checkpoint proteins is effective in adult cancers but has shown limited efficacy in pediatric cancers. While factors regulating expression of immune checkpoint proteins such as PD-L1 are w...
Bo Zhang,Ye Zhang,Tao Wang et al. Bo Zhang et al.
This study investigated the association between serum Klotho levels and all-cause mortality in postmenopausal women. Utilizing data from 3,448 postmenopausal women in the US National Health and Nutrition Examination Survey (NHANES) from 200...
Xinrong Li,Wenwen Si,Zhan Li et al. Xinrong Li et al.
Subsequently to the publication of the above paper, an interested reader drew to the authors' attention that, for the JC‑1 staining experiments shown in Fig. 5F on p. 9, the 'mimic NC' and 'inhibitor' panels appeared to show the same cells...
Hejiao Zhang,Qiang Hu,Yong Zhang et al. Hejiao Zhang et al.
Alcohol-associated liver disease (ALD) is a prevalent global health issue primarily caused by excessive alcohol consumption. Recent studies have highlighted the gut-liver axis's protective role against ALD, mainly through gut microbiota. Ho...
Han Lei,Zhengwei Zhou,Chang Liu et al. Han Lei et al.
Background: Cuproptosis, a novel form of cell death triggered by copper ion accumulation, has shown potential in cancer therapy, particularly through the involvement of cuproptosis-related lnRNAs (CRLs). In-depth analyses...
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