Dysregulation of microRNA (miRNA) Due to Phthalate/Phthalate Metabolite Exposure and Associated Health Effects: A Narrative Review [0.03%]
酞酸盐/酞酸盐代谢物暴露引起的微小核糖核酸（miRNA）失调及其相关健康效应：叙述性综述
Aamer Mohammed,Stephen L Atkin,Edwina Brennan
Aamer Mohammed
Phthalates, a group of synthetic non-persistent organic chemicals commonly used as solvents and plasticisers, have been associated with a range of detrimental health effects. These endocrine disrupting chemicals (ECDs) may exert their effec...
Sex-Specific Dysregulation of Cardiac-Enriched MicroRNAs with Age in Drosophila melanogaster [0.03%]
果蝇衰老过程中性别特异的心肌微RNA失调
Lijo N Varghese,Philip Sheard,Daryl O Schwenke et al.
Lijo N Varghese et al.
Introduction: Dysregulation of cardiac-enriched microRNA (miRNA) expression is linked to age-associated cardiovascular diseases (CVDs). However, the sex-specificity and age at which dysregulation occurs remain unclear. Given the conserved n...
Dysregulation of MiR-21, MiR-221 and MiR-451 During Neoadjuvant Treatment of Breast Cancer: A Prospective Study [0.03%]
乳腺癌新辅助治疗过程中MiR-21、MiR-221和MiR-451的失调：一项前瞻性研究
Carine Bispo Patury,Brenda Luanny Maia Santos,Anna Lucia Carvalho Matos et al.
Carine Bispo Patury et al.
Background: Breast cancer is highly heterogeneous disease in which different responses are observed to the same treatment for different subtypes and extents of similar diseases. Considering this scenario, the search for t...
Observational Study
Biomolecules. 2024 Dec 11;14(12):1580. DOI:10.3390/biom14121580 2024
Stefano Zoroddu,Angela Lucariello,Antonio De Luca et al.
Stefano Zoroddu et al.
MicroRNAs (miRNAs) are pivotal regulators of gene expression, influencing key cellular processes such as proliferation, differentiation, apoptosis, and metastasis. In the realm of sarcomas-a diverse group of malignant tumors affecting soft ...
Dengue virus NS1 hits hard at the barrier integrity of human cerebral microvascular endothelial cells via cellular microRNA dysregulations [0.03%]
登革病毒NS1通过细胞微小核糖核酸失调重创人脑微血管内皮细胞屏障功能
Apoorva,Atul Kumar,Sunit K Singh
Apoorva
Dengue virus (DENV) infections are commonly reported in the tropical and subtropical regions of the world. DENV is reported to exploit various strategies to cross the blood-brain barrier. The NS1 protein of DENV plays an important role in v...
MiRNA Dysregulation in Brain Injury: An In Silico Study to Clarify the Role of a MiRNA Set [0.03%]
脑损伤中MiRNA失调的组学和计算研究：通过生物信息学和网络分析确定一组miRNA的作用机制
Francesco Sessa,Cristoforo Pomara,Flavia Schembari et al.
Francesco Sessa et al.
Background: The identification of specific circulating miRNAs has been proposed as a valuable tool for elucidating the pathophysiology of brain damage or injury and predicting patient outcomes. ...
Micro RNA Dysregulation in Keratinocyte Carcinomas: Clinical Evidence, Functional Impact, and Future Directions [0.03%]
基底细胞癌和鳞状细胞癌中异常表达的微小核糖核酸：临床证据、功能影响及未来研究方向
Jessica Conley,Benjamin Genenger,Bruce Ashford et al.
Jessica Conley et al.
The keratinocyte carcinomas, basal cell carcinoma (BCC), and cutaneous squamous cell carcinoma (cSCC), are the most common cancers in humans. Recently, an increasing body of literature has investigated the role of miRNAs in keratinocyte car...
MicroRNA dysregulation in glutamate and dopamine pathways of schizophrenia: From molecular pathways to diagnostic and therapeutic approaches [0.03%]
精神分裂症中谷氨酸和多巴胺通路的微小核糖核酸失调：从分子途径到诊断和治疗措施
Parya Alizadeh Khosroshahi,Mohammad Ghanbari
Parya Alizadeh Khosroshahi
Schizophrenia is a complex psychiatric disorder, and genetic and environmental factors have been implicated in its development. Dysregulated glutamatergic and dopaminergic transmission pathways are involved in schizophrenia development. Bes...
Exploring the intricate relationship between miRNA dysregulation and breast cancer development: insights into the impact of environmental chemicals [0.03%]
探究microRNA失调与乳腺癌发展之间的复杂关系：环境化学物质影响的启示
Narges Abolhasanzadeh,Sajed Sarabandi,Bahar Dehghan et al.
Narges Abolhasanzadeh et al.
Breast cancer stands as the most prevalent form of cancer among women globally, influenced by a combination of genetic and environmental factors. Recent studies have investigated changes in microRNAs (miRNAs) during breast cancer progressio...
MicroRNA Dysregulation in Early Breast Cancer Diagnosis: A Systematic Review and Meta-Analysis [0.03%]
微小核糖核酸在乳腺癌早期诊断中的失调：系统评价和Meta分析
Alejandro Garrido-Palacios,Ana María Rojas Carvajal,Ana María Núñez-Negrillo et al.
Alejandro Garrido-Palacios et al.
Breast cancer continues to be the leading cause of death in women worldwide. Mammography, which is the current gold standard technique used to diagnose it, presents strong limitations in early ages where breast cancer is much more aggressiv...
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