Differential impact of microcystins MC-LR and [D-Leu1]MC-LR in different areas of the rat brain after chronic exposure: oxidative stress and antioxidant responses [0.03%]
慢性暴露后微囊藻毒素MC-LR和[D-Leu1]MC-LR对大鼠脑不同区域的差异化影响:氧化应激与抗氧化响应
Hernando Marcelo,Cogo Pagella Joaquín,de la Rosa Florencia et al.
Hernando Marcelo et al.
Cyanotoxins are a significant concern due to their frequent presence in Southamerica waters. While numerous studies have investigated the toxic effects of MC-LR, knowledge regarding the toxicity of [D-Leu1]MC-LR remains limited. The aim of ...
Insight into the Molecular Mechanism for the Discrepant Inhibition of Microcystins (MCLR, LA, LF, LW, LY) on Protein Phosphatase 2A [0.03%]
微囊藻毒素(MC-LR, LA, LF, LW, LY)对蛋白磷酸酶2A抑制差异的分子机制研究
Yixue Xu,Jiyuan Cui,Huiqun Yu et al.
Yixue Xu et al.
Microcystins (MCs) exhibit diversified inhibition effects on protein phosphatases (PPs) due to their structural differences. To fully evaluate the potential mechanism for the discrepant inhibition effects, the five most frequent MCs with va...
Biochar-amended constructed wetlands for eutrophication control and microcystin (MC-LR) removal [0.03%]
生物炭改良人工湿地控制富营养化和去除微囊藻毒素(MC-LR)
Rui Cheng,Shengnan Hou,Jingfu Wang et al.
Rui Cheng et al.
Microcystins (MCs) pollution caused by eutrophication and climate change has posed a serious threat to ecosystems and human health. Constructed wetlands (CWs) with biochar addition volume ratios of 0% (BC0-CWs), 10% (BC10-CWs), 20% (BC20-CW...
Treatment of microcystin (MC-LR) and nutrients in eutrophic water by constructed wetlands: Performance and microbial community [0.03%]
构建的湿地对富营养化水中微囊藻毒素(MC-LR)和营养盐去除效果及微生物群落的影响
Rui Cheng,Hui Zhu,Brian Shutes et al.
Rui Cheng et al.
Cyanobacterial harmful algal blooms and microcystins (MCs) pollution pose serious threat to aquatic ecosystem and public health. Planted and unplanted constructed wetlands (CWs) filled with four substrates (i.e., gravel (G-CWs), ceramsite (...
Isolation and Characterization of Lake Erie Bacteria that Degrade the Cyanobacterial Microcystin Toxin MC-LR [0.03%]
分离和鉴定降解蓝藻微囊藻毒素MC-LR的埃里湖细菌
Alison Thees,Ealla Atari,Johnna Birbeck et al.
Alison Thees et al.
Microcystin-LR (MC-LR) is a cyclic hepatotoxin produced by cyanobacteria, including Microcystis sp. and Planktothrix sp. Harmful algal blooms (HABs) in Lake Erie have become a major human health concern in recent years, highlighted by the A...
Combined Effects of Temperature and the Microcystin MC-LR on the Feeding Behavior of the Rotifer Brachionus calyciflorus [0.03%]
温度和微囊藻毒素MC-LR对萼花臂尾轮虫摄食行为的联合影响
Xian-Ling Xiang,Ying-Ying Chen,Qiu-Lei Xu et al.
Xian-Ling Xiang et al.
The aim of this study was to investigate the responses in filtration and grazing rates of five rotifer strains of the species Brachionus calyciflorus under different temperatures and MC-LR concentrations. The results showed that strain iden...
Acute effects of microcystins MC-LR and MC-RR on acid and alkaline phosphatase activities and pathological changes in intraperitoneally exposed tilapia fish (Oreochromis sp.) [0.03%]
微囊藻毒素MC-LR和MC-RR对腹腔注射暴露的鱼(奥利亚罗非鱼)酸性磷酸酶和碱性磷酸酶活性及病理变化的急性效应研究
Loyda Atencio,Isabel Moreno,Ana I Prieto et al.
Loyda Atencio et al.
Microcystins (MC) are frequently present in cyanobacterial blooms in rivers and lakes, increasing the risk of toxicity to both animals and humans. There more than eighty reported microcystins, and the present study was undertaken to determi...
Method for detecting classes of microcystins by combination of protein phosphatase inhibition assay and ELISA: comparison with LC-MS [0.03%]
结合蛋白质磷酸酶抑制测定和ELISA检测微囊藻毒素MC-LR和YR混合体的方法及其与LC-MS法的比较研究
Douglas O Mountfort,Patrick Holland,Jan Sprosen
Douglas O Mountfort
Depending on the class of microcystin the protein phosphatase inhibition assay shows different sensitivities to different classes of toxin. We have determined that the IC50 values obtained from dose-response curves for the inhibition of the...