Heterogeneous characteristics of γδ T cells in peripheral blood of diffuse large B-cell lymphoma [0.03%]
弥漫性大B细胞淋巴瘤外周血γδT细胞的异质性特征分析
Peng-Lin Wang,Wen-Pu Lai,Jia-Mian Zheng et al.
Peng-Lin Wang et al.
Background: Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous disease with variable clinical and molecular features. Studies have highlighted the significant role of γδ T cells in the survival of leukemia ...
Characterizing microglial heterogeneity in autophagy impairment of Paraquat-induced Parkinson's disease-like neurodegeneration [0.03%]
百草枯诱导的帕金森氏病样神经退行性疾病中自噬损伤的小胶质细胞异质性特征研究
Yu Zhang,Yihua Jiang,Zhen Yu et al.
Yu Zhang et al.
Parkinson's disease (PD) is a prevalent neurodegenerative condition influenced by environmental elements, notably Paraquat (PQ), which is one of the known risk factors. Impaired autophagy is a critical factor in the pathogenesis of PD, yet ...
Not All Itch Is Created Equal in Atopic Dermatitis: A Prospective Observational Study of the Heterogeneous Characteristics of Itch [0.03%]
特应性皮炎患者的瘙痒千差万别：一项关于瘙痒异质性的前瞻性观察研究
Brandon Ansbro,Jonathan I Silverberg
Brandon Ansbro
Background: Although itch is the universal symptom of atopic dermatitis (AD), little is known about its clinical phenotypes in AD. Objective: To examine the relationships of itch characteristics and patterns with AD severity, mental health,...
Proteomics-based characterization of ribosome heterogeneity in adult mouse organs [0.03%]
基于蛋白质组学的成年小鼠器官核糖体异质性特征分析
Marie R Brunchault,Anne-Marie Hesse,Julia Schaeffer et al.
Marie R Brunchault et al.
The translation process, leading to protein synthesis from mRNA, has been long thought to be invariable in all cellular organisms. Increasing evidence shows that it is finely regulated by variable features of the translation machinery. Nota...
Heterogeneity of early-onset conduct problems: assessing different profiles, predictors and outcomes across childhood [0.03%]
儿童期早期品行问题的异质性：评估不同的亚型、预测因素和结果
Beatriz Díaz-Vázquez,María Álvarez-Voces,Estrella Romero et al.
Beatriz Díaz-Vázquez et al.
Background: Among early-onset conduct problems (CP), associated with more disruptive behaviors of greater intensity and stability, several domains have been proposed from a variable-centered perspective to capture their h...
A machine learning approach for type 2 diabetes diagnosis and prognosis using tailored heterogeneous feature subsets [0.03%]
基于个性化异构特征子集的2型糖尿病诊断和预后机器学习方法
J Ramón Navarro-Cerdán,Pedro Pons-Suñer,Laura Arnal et al.
J Ramón Navarro-Cerdán et al.
Type 2 diabetes (T2D) is becoming one of the leading health problems in Western societies, diminishing quality of life and consuming a significant share of healthcare resources. This study presents machine learning models for T2D diagnosis ...
Unsupervised Deep Learning of Electronic Health Records to Characterize Heterogeneity Across Alzheimer Disease and Related Dementias: Cross-Sectional Study [0.03%]
电子健康记录的无监督深度学习在阿尔茨海默病及相关痴呆症异质性特征描述中的应用：横断面研究
Matthew West,You Cheng,Yingnan He et al.
Matthew West et al.
Background: Alzheimer disease and related dementias (ADRD) exhibit prominent heterogeneity. Identifying clinically meaningful ADRD subtypes is essential for tailoring treatments to specific patient phenotypes. ...
Characterizing the molecular and spatial heterogeneity of midline gliomas in adults: a single institution analysis [0.03%]
成人中线胶质瘤的分子和空间异质性特征：单中心分析
Bryan J Neth,Robert M Kraft,Kathryn L Eschbacher et al.
Bryan J Neth et al.
Purpose: Primary gliomas arising within midline structures of the central nervous system are associated with a worse prognosis compared with hemispheric gliomas. In adults, compared to their pediatric counterparts, adult ...
Characterizing heterogeneity in Alzheimer's disease progression: a semiparametric model [0.03%]
阿尔茨海默病进展的异质性特征：半参数模型方法
Fatih Gelir,Suneel Babu Chatla,Md Shenuarin Bhuiyan et al.
Fatih Gelir et al.
The progression of Alzheimer's disease (AD), a leading cause of dementia worldwide, is known for its variability and complexity, challenging the conventional methods of monitoring and predicting disease trajectories. This study introduces a...
Characterizing the heterogeneity of Castleman disease and oligocentric subtype: Findings from the ACCELERATE registry [0.03%]
Castleman疾病及其寡中心型亚型的异质性特征：来自ACCELERATE注册研究的发现
Sheila K Pierson,Joshua D Brandstadter,Drew Torigian et al.
Sheila K Pierson et al.
Castleman disease (CD) describes a group of rare lymphoproliferative disorders that exhibit a wide range of symptomatology and degree of lymphadenopathy, particularly across the two forms of CD with unknown etiology, unicentric CD (UCD) and...
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