BCAA catabolism targeted therapy for heart failure with preserved ejection fraction [0.03%]
针对射血分数保留的心力衰竭的支链氨基酸分解代谢靶向治疗
Meng Wang,Zhao Liu,Shuxun Ren et al.
Meng Wang et al.
Rationale: Heart failure with preserved ejection fraction (HFpEF) is a major unmet medical need with limited effective treatments. A significant contributing factor to HFpEF, a multifactorial disease, is underlying metabolic dysfunction. Wh...
Non-calcified Coronary Plaque Burden is Related to Epicardial Adipose Tissue and Peri-coronary Adipose Tissue Attenuation in Heart Failure With Preserved Ejection Fraction [0.03%]
非钙化冠状动脉斑块负担与心力衰竭伴射血分数保留的外膜脂肪组织和冠状周围脂肪组织衰减有关
Ana C Iribarren,Haider Aldiwani,Panteja Rezaeian et al.
Ana C Iribarren et al.
Left Ventricular Ejection Fraction and Previous Cardiac Revascularization: Impact on Patient Survival, Graft Survival, and Complications in Kidney Transplant Recipients [0.03%]
左心室射血分数与既往冠脉再血管化对肾移植患者生存、移植物功能及并发症的影响：列线图预测模型的建立与验证
Dominic Amara,Miguel Nunez,Justin Parekh et al.
Dominic Amara et al.
Background: Kidney transplant physicians believe that the cardiac status of kidney transplant recipients influences posttransplant outcomes. However, the Scientific Registry of Transplant Recipients (SRTR) does not includ...
Efficacy of Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors in Heart Failure With Preserved Ejection Fraction: A Systematic Review [0.03%]
钠-葡萄糖共转运蛋白2(SGLT2)抑制剂对射血分数保留心力衰竭疗效的系统评价
María Victoria Santos Guzmán,Daimi Rivera,Isabella Marian Reyna Guerrero et al.
María Victoria Santos Guzmán et al.
Heart failure with preserved ejection fraction (HFpEF) represents a growing clinical challenge with limited therapeutic options. Sodium-glucose cotransporter 2 (SGLT2) inhibitors have recently emerged as a promising intervention; however, t...
Flecainide Toxicity Leading to Transient Heart Failure With Reduced Ejection Fraction: A Case Study [0.03%]
氟卡尼中毒导致射血分数降低性心衰的个案研究
Trevor Wolchover,Leili Pourafkari,Vishva Dev et al.
Trevor Wolchover et al.
Flecainide, a class Ic antiarrhythmic, has been widely prescribed for managing cardiac arrhythmias. While effective in rhythm control, there is growing, albeit limited, evidence of its association with reversible heart failure with reduced ...
Case Reports
Cureus. 2025 May 14;17(5):e84100. DOI:10.7759/cureus.84100 2025
Efficacy and safety of once-daily oral semaglutide in patients with heart failure with preserved ejection fraction, type 2 diabetes and obesity: a real-world study [0.03%]
一次每日口服塞马鲁肽治疗射血分数保留型心力衰竭、2 型糖尿病和肥胖患者的疗效及安全性：一项真实世界研究
Alicia Trenas,Miguel A Pérez-Velasco,Maria-Rosa Bernal-López et al.
Alicia Trenas et al.
Background: There is limited evidence on the role of glucagon-like peptide-1 receptor agonists in heart failure. This work analyzes the efficacy of once-daily oral semaglutide in terms of health status and change in body ...
Effects of Heat Therapy on Exercise Tolerance in a Rat Model of Heart Failure with Preserved Ejection Fraction [0.03%]
热疗对射血分数保留型心力衰竭大鼠运动耐受性的影响
Michael D Belbis,Bohyun Ro,Luke E Schepers et al.
Michael D Belbis et al.
Heart failure with preserved ejection fraction (HFpEF) impairs cardiac and skeletal muscle function, reducing exercise tolerance. Few therapies are available to improve physical capacity in HFpEF. We tested the hypothesis that chronic whole...
Heart failure hospitalisation from recurrent AF is uncommon following catheter ablation in patients with HFrEF [0.03%]
对于射血分数降低的心力衰竭患者，导管消融后房颤复发导致心力衰竭住院少见
Kenneth Cho,Sandeep Prabhu,Louise Segan et al.
Kenneth Cho et al.
Background: Heart failure with reduced ejection fraction (HFrEF) in the presence of atrial fibrillation (AF) is common, with concerns AF recurrence will precipitate acute decompensation. However, the impact of AF recurren...
Venous Excess Ultrasound (VExUS) score and short-term outcomes in ambulatory patients with heart failure with reduced ejection fraction: an exploratory study [0.03%]
静脉超量负荷超声(VExUS)评分与射血分数降低型心力衰竭门诊患者的短期预后：一项探索性研究
Ahmed Hassan,Ahmed A Khalil,Amir Mostafa et al.
Ahmed Hassan et al.
Background: Venous congestion significantly contributes to morbidity and mortality in heart failure with reduced ejection fraction (HFrEF). The Venous Excess Ultrasound (VExUS) score, a multi-parameter sonographic assessm...
Evaluation of the 6-Month Effect of Sacubitril-Valsartan Compared to ACEI and ARB on LVEF in Heart Failure Patients: A Double-Blind Randomized Clinical Trial [0.03%]
沙库必曲缬沙坦与ACEI或ARB比较对心力衰竭患者LVEF影响的6个月双盲随机临床试验评价
Farnosh Masmoo,Farnaz Fariba,Nakissa Khansari et al.
Farnosh Masmoo et al.
Background and aim: Heart failure is a common condition that affects millions of people worldwide. The aim of this study was to evaluate the 6-month effect of sacubitril-valsartan (SV) compared to angiotensin-converting e...
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