Tailoring multidomain intervention programs to reduce cognitive and physical decline in older adults: Examining rural-urban differences in a nationwide cluster-randomized controlled trial [0.03%]
针对农村和城市地区差异制定多领域干预项目以减少老年人的认知和身体功能下降：一项全国范围集群随机对照试验的研究
Min-Yin Ho,Wei-Ju Lee,Ko-Han Yen et al.
Min-Yin Ho et al.
Background: Frailty and cognitive impairment are major challenges in aging populations. Multidomain interventions targeting physical, cognitive, and nutritional health show promise; however, evidence on rural-urban differ...
Effects of Oral Nutrition Supplementation with or Without Multi-Domain Intervention Program on Cognitive Function and Overall Health in Older Adults: A Randomized Controlled Trial [0.03%]
口服营养补充联合多领域干预对老年人认知功能和整体健康的影响：一项随机对照试验
Hae-Jin Kang,Eun-Hye Lee,Seong-Hye Choi et al.
Hae-Jin Kang et al.
Objectives: The global rise in dementia prevalence is escalating the socioeconomic burden, prompting efforts in prevention and treatment. This study aimed to evaluate the effects of an 8-week oral nutrition supplement (ONS) program with or ...
Randomized Controlled Trial
Nutrients. 2025 Jun 5;17(11):1941. DOI:10.3390/nu17111941 2025
Genetic background and multidomain interventions in mild cognitive impairment [0.03%]
遗传背景和轻度认知障碍的多领域干预措施
Kosuke Fujita,Tetsuaki Kimura,Akiko Yamakawa et al.
Kosuke Fujita et al.
Background: The growing prevalence of dementia emphasizes the need for effective prevention strategies. Although the partial efficacy of multidomain interventions for dementia prevention has been demonstrated, understandi...
Randomized Controlled Trial
Alzheimer's research & therapy. 2025 Jun 10;17(1):130. DOI:10.1186/s13195-025-01764-0 2025
[Mild cognitive impairment and the importance of diagnosis in light of new anti-amyloid monoclonal antibodies for treating Alzheimer's disease, as well as the significance of multidomain lifestyle interventions in preventing dementia] [0.03%]
[轻度认知障碍及新的抗淀粉样蛋白单克隆抗体治疗阿尔茨海默病时代的诊断重要性——以及多领域生活方式干预在预防痴呆方面的作用]
Gudny Stella Gudnadottir
Gudny Stella Gudnadottir
The cost effectiveness of a multidomain intervention on physical, cognitive, vascular, dietary and psychosocial outcomes among community dwelling older adults with cognitive frailty in Malaysia: The AGELESS Trial [0.03%]
马来西亚认知脆弱性社区老年人多领域干预的成本效益分析：AGELESS试验报告物理、认知、血管、饮食和心理社会成果的影响
Pavapriya Ponvel,Suzana Shahar,Devinder Kaur Ajit Singh et al.
Pavapriya Ponvel et al.
Background: Cognitive frailty (CF) in older adults is a potentially reversible syndrome that may benefit from lifestyle-based multidomain interventions. This study assessed the AGELESS intervention's impact on cognitive, ...
Randomized Controlled Trial
Alzheimer's research & therapy. 2025 May 13;17(1):101. DOI:10.1186/s13195-025-01722-w 2025
Multidomain intervention for delaying aging in community-dwelling older adults (MIDA): study design and protocol [0.03%]
针对社区老年人延缓衰老的多领域干预研究——MIDA研究方案
Siyang Lin,Fang Wang,Min Huang et al.
Siyang Lin et al.
Background: The exploration of interventions to delay aging is an emerging topic that promotes healthy aging. The multidomain intervention has the potential to be applied in the field of aging because it concentrates on t...
Randomized Controlled Trial
Annals of medicine. 2025 Dec;57(1):2496409. DOI:10.1080/07853890.2025.2496409 2025
Multi-domain intervention program on cognitive function in community-dwelling older adults: Pilot study [0.03%]
社区老年人认知功能综合干预方案的试点研究
Rosalinda Sánchez-Arenas,Israel Grijalva,Leticia Manuel-Apolinar et al.
Rosalinda Sánchez-Arenas et al.
Background: Recent interventions to prevent cognitive impairment include aerobic-cognitive training and educational programs on cognitive function. Object...
Longitudinal deterioration of subjective cognitive decline in apolipoprotein ε4 carriers and improvement of subjective cognitive decline by multi-domain intervention for prevention of dementia: The cognitive function instrument assessment [0.03%]
载脂蛋白ε4携带者主观认知下降的纵向衰退及多领域干预改善主观认知下降的预防痴呆：一项基于认知功能量表评估的研究
Tohmi Osaki,Yutaro Oki,Ryoko Kumagai et al.
Tohmi Osaki et al.
BackgroundSubjective cognitive decline represents an early stage of mild cognitive impairment, with the Cognitive Function Instrument (CFI) serving to subjectively evaluate the decline in daily living activities associated with this minor c...
Recruitment and retention in a multidomain intervention for post-TIA and minor stroke: turning challenges into lessons [0.03%]
针对TIA和轻微卒中的多领域干预中人员的招募与保留：化挑战为经验
Micaela Gonçalves,Ana Rute Costa,Maria João Lima et al.
Micaela Gonçalves et al.
Feasibility of a Multidomain Intervention for Safe Mobility in People with Parkinson's Disease and Recurrent Falls [0.03%]
帕金森病和反复跌倒的人安全多领域干预措施的可行性研究
Natalie E Allen,Lina Goh,Colleen G Canning et al.
Natalie E Allen et al.
Objective: Mobility limitations and falls are common in people with Parkinson's disease (PwP). A tailored, multidomain intervention has the potential to be more effective in improving mobility safety and preventing falls ...
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