Donor liver natural killer cells ameliorate liver allograft rejection via inducing apoptosis of alloreactive CD8+ T cells generating CD4+CD25+ regulatory T cells [0.03%]
捐献者肝脏中的自然杀伤细胞可通过诱导allo-reactive CD8+T细胞凋亡及生成CD4+CD25+调节性T细胞来缓解同种异体移植排斥反应
Jiandong Yu,Jiayan Wu,Tianzhu Long et al.
Jiandong Yu et al.
The roles of donor liver natural killer (NK) cells in allogeneic liver transplantation remains controversial. Herein, we investigated the effects of liver NK cells on liver allograft tolerance by using liver NK cells and allogeneic spleen T...
A COVERED CORONARY STENT FOR ACUTE PERFORATION AFTER A PERCUTANEOUS CORONARY INTERVENTION DUE TO CARDIAC ALLOGRAFT VASCULOPATHY [0.03%]
心脏同种异体移植血管病冠状动脉介入治疗后急性穿孔的药物洗脱支架植入一例
Mario Udovičić,Hrvoje Falak,Miro Raguž et al.
Mario Udovičić et al.
Cardiac allograft vasculopathy (CAV) is diffuse concentric narrowing caused by intimal fibriproliferation of the coronary arteries in patients after heart transplantation (HTx). It affects almost one third of patients over the period of 5 y...
Development of an ensemble prediction model for acute graft-versus-host disease in allogeneic transplantation based on machine learning [0.03%]
基于机器学习的异基因移植急性移植物抗宿主病列队预测模型构建
Lin Song,Xingwei Wu,Mengjia Xu et al.
Lin Song et al.
Background: Acute graft-versus-host disease (aGVHD) is a major post-transplantation complication and one of the most significant causes of non-relapse-related death. However, the massive and complex clinical data make aGV...
Type 1 interferon signature and allograft inflammatory factor-1 contribute to refractoriness to TNF inhibition in ankylosing spondylitis [0.03%]
I型干扰素信号和同种异体移植物炎症因子-1导致强直性脊柱炎对TNF抑制产生耐药性
Woogil Song,Eunyoung Emily Lee,Seongwan Park et al.
Woogil Song et al.
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis that primarily affects the enthesis and may culminate in bony ankylosis of the spine. Despite TNF inhibitor (TNFi) being foundational in managing active inflammation, 30-40% of...
Combined cellular and antibody-mediated rejection of orthotopic heart transplant following influenza A infection [0.03%]
甲型流感病毒感染后心脏移植的同种异体移植排斥反应
Joseph Crowder,Jeffrey F Spindel,Nathan Shelman et al.
Joseph Crowder et al.
Viral infections have been associated with acute allograft rejection in solid organ transplant recipients. Influenza infection upregulates host proinflammatory cytokines, suggesting the host immune response can precipitate graft rejection. ...
Case Reports
BMJ case reports. 2025 Jul 1;18(7):e265384. DOI:10.1136/bcr-2025-265384 2025
Sustained Molecular Allograft Injury After Episodes of Acute Rejection and Organizing Pneumonia Increases the Risk of Lung Allograft Failure [0.03%]
急性排斥反应和机化性肺炎发作后的持续分子异体移植损伤会增加肺移植失败的风险
Michael B Keller,Allison Y Lin,Moon Kyoo Jang et al.
Michael B Keller et al.
Background: Despite treatment of major risk factors such as acute rejection (AR) and organizing pneumonia (OP) in lung transplant recipients, chronic lung allograft dysfunction (CLAD) still develops at high rates, suggest...
Early and Late Application of Skin Homograft in Management of Major Burn Patients: A Comparative Study [0.03%]
大面积烧伤病人治疗中自体皮移植早晚期效果的比较研究
M A Megahed,H R A Elkhouly
M A Megahed
Our objective is to compare the effect of early and late application of skin homograft regarding complications and mortality rate. Burn is a type of physical trauma to skin or tissue. Burn can lead to loss of skin, resulting in deep, widesp...
Production and Characterization of Threads and Textiles Made from Cell-Assembled Extracellular Matrix: Translation from Human to Ovine Cells to Support Allogeneic Studies [0.03%]
基于细胞组装的细胞外基质纤维和纺织品的制备及表征:从人细胞到绵羊细胞的研究以支持同种异体移植研究
Yoann Torres,Maude Gluais,Nicolas Da Silva et al.
Yoann Torres et al.
We previously developed a human and completely biological tissue-engineered vascular graft (TEVG) to overcome synthetic material limitations. Using a textile-inspired assembly method, TEVGs were woven from threads of cell-assembled extracel...
Daratumumab plus bortezomib and dexamethasone as a bridge to allogeneic transplantation in refractory T-cell lymphoblastic lymphoma [0.03%]
达雷妥尤单抗联合硼替佐米和地塞米松用于难治性T细胞淋巴母细胞淋巴瘤的移植过渡治疗
Alessio Maria Edoardo Maraglino,Simona Sammassimo,Ginevra Lolli et al.
Alessio Maria Edoardo Maraglino et al.
Relapsed and refractory (r/r) T-cell lymphoblastic lymphoma (T-LBL) is a highly lethal disease, with no effective treatment options. Daratumumab, an anti-CD38 human IgG1κ monoclonal antibody has been used as single agent in CD38 positive r...
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