ΔN-TRPV1: A Molecular Co-detector of Body Temperature and Osmotic Stress [0.03%]
ΔN-TRPV1：体温和渗透压应激的分子共检测器
Cristian Zaelzer,Pierce Hua,Masha Prager-Khoutorsky et al.
Cristian Zaelzer et al.
Thirst and antidiuretic hormone secretion occur during hyperthermia or hypertonicity to preserve body hydration. These vital responses are triggered when hypothalamic osmoregulatory neurons become depolarized by ion channels encoded by an u...
The role of Ca2+/calmodulin-stimulable adenylyl cyclases as molecular coincidence detectors in memory formation [0.03%]
Ca2+/钙调素激活的腺苷酸环化酶在记忆形成中作为分子联结探测器的作用
N Mons,J L Guillou,R Jaffard
N Mons
Evidence from systems as diverse as mollusks, insects and mammals has revealed that adenylyl cyclase, cyclic adenosine 3',5'-monophosphate (cAMP) cascade, cAMP-dependent protein kinases and their substrates are required for the cellular eve...
Signal integration in the nervous system: adenylate cyclases as molecular coincidence detectors [0.03%]
神经系统中的信号整合：环核苷酸门控离子通道和腺苷酸环化酶作为分子联合检测器
R R Anholt
R R Anholt
Integrating multiple incoming messages simultaneously and discriminating 'meaningful' signals from spontaneous neural activity represent central problems to the nervous system. One mechanism by which signal integration and signal-to-noise r...