N J Shaheen,D A Patel,I Abeynayake et al. N J Shaheen et al.

Erosive esophagitis (EE) is a common complication of gastroesophageal reflux disease. Guidelines support long-term proton pump inhibitor (PPI) therapy to relieve symptoms and maintain healing of EE. Ideally, patients remain on their first l...

Prateek Sharma,Michael Vaezi,Peter Unge et al. Prateek Sharma et al.

Background: Linaprazan glurate, a potassium-competitive acid blocker, is in development for the treatment of erosive oesophagitis and other acid-related diseases. ...

Nam Hee Kim,Yoosoo Chang,Seungho Ryu et al. Nam Hee Kim et al.

Background/aims: We aim to compare the remission of erosive esophagitis (EE) among individuals with different phenotypes based on their metabolic health and obesity status and investigate the impact of changes in metaboli...

Colin W Howden,Philip Katz,Kenneth R DeVault et al. Colin W Howden et al.

Background: Patients with erosive oesophagitis, and those with persistent symptomatic non-erosive gastro-oesophageal reflux disease, require long-term maintenance treatment with acid-suppressing agents. ...

Sang Pyo Lee,In-Kyung Sung,Oh Young Lee et al. Sang Pyo Lee et al.

Background/aims: Fexuprazan, a novel potassium-competitive acid blocker, was developed for treating acidrelated disorders. Pharmacokinetic and pharmacodynamic properties of fexuprazan, unlike those of proton pump inhibito...

Cheol Min Shin,Suck Chei Choi,Jin Woong Cho et al. Cheol Min Shin et al.

Background: The aims of this study were to confirm the non-inferiority of tegoprazan to lansoprazole up to week 4 in patients with erosive esophagitis (EE) and to evaluate its effectiveness in rapid mucosal healing and sy...

Hyun Tak Lee,Hyesun Hong,Ah Young Lee et al. Hyun Tak Lee et al.

Introduction: Insulin resistance is a key factor in metabolic syndrome. Identifying indicators of insulin resistance through endoscopic findings could be valuable in assessing a patient's systemic metabolic status. Thus, ...

Yuchul Jeong,Beom Jun Lee,Se-Hyeon Han Yuchul Jeong

The Journal of Clinical Medicine retracts the article entitled "A Phase III Head-to-Head Study to Compare the Efficacy and Safety of Fexuprazan and Esomeprazole in Treating Patients with Erosive Esophagitis" [...].

Huiyun Zhu,Qian Xue,Yingxiao Song et al. Huiyun Zhu et al.

Background: An evidence gap still exists regarding the efficacy and safety of tegoprazan in Chinese patients with erosive esophagitis (EE) in China. This study aimed to verify the efficacy and safety of tegoprazan vs. eso...

Tao He,Xiao-Yu Sun,Meng-Han Tong et al. Tao He et al.

Background and aim: Obesity is association with elevated risks of erosive esophagitis (EE), and metabolic abnormalities play crucial roles in its development. The aim of the study was to assess the association between met...