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Toshihito Hirai,Taro Banno,Kazuya Omoto et al. Toshihito Hirai et al.
Background: Donor-derived cell-free DNA (dd-cfDNA) offers a non-invasive biomarker for detecting allograft injury. However, its performance in predominantly living-donor transplant settings in Asian populations remains un...
Dana Dlouha,Sarka Chytilova,Jevgenija Vymetalova et al. Dana Dlouha et al.
Plasma circulating donor-derived cell-free DNA (ddcfDNA) can be used to noninvasively monitor acute rejection of heart transplants (HTx). This study utilized digital droplet PCR to analyze ddcfDNA concentrations (measured in copies per mill...
Yiwu Zhong,Xu Hu,Xiaoping Li et al. Yiwu Zhong et al.
In the field of liver disease treatment, liver transplantation (LT) has become an effective option for end-stage liver disease. However, issues such as immune rejection and graft damage remain important factors influencing the success rate ...
Jens Böhmer,Håkan Wåhlander,Karin Tran-Lundmark et al. Jens Böhmer et al.
Objective: Traditional rejection surveillance after heart transplantation (HTx) is based on endomyocardial biopsies (EMB), which are invasive, expensive and associated with complications. Monitoring using cell-free DNA (c...
Jessica Tang,Lior Kashani Ligumsky,Kate Woodruff et al. Jessica Tang et al.
Background: Pregnant kidney transplant recipients (KTRs) are a vulnerable, high-risk population, susceptible to obstetrical complications, as well as graft rejection. Current methods used to monitor kidney transplant func...
George E Nita,Fotini Partheniou,Dan Ridgway et al. George E Nita et al.
Background: Monitoring donor-derived cell-free DNA (dd-cfDNA) is a promising noninvasive method for assessing allograft health in renal transplant recipients. This UK pilot study evaluated a novel insertion and deletion (...
Ananth V Charya,Moon K Jang,Hyesik Kong et al. Ananth V Charya et al.
Donor-derived cell-free DNA is increasingly used in clinical practice to monitor lung transplant patients for acute rejection. However, its association with conventional approaches to monitor immunosuppression remains unclear. This multicen...
Elena Cuadrado-Payán,Eva González-Roca,Diana Rodríguez-Espinosa et al. Elena Cuadrado-Payán et al.
Background and objective: The introduction of donor-derived free DNA (ddcfDNA) has emerged as an accurate non-invasive biomarker to diagnose rejection, compared to classical ones. Here we evaluate our experience after its...
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