Donor-Derived Cell-Free DNA for Diagnosing Subclinical Rejection: A Pilot Multicenter Study in Japanese Living-Donor Kidney Transplantation [0.03%]
供者来源的无细胞DNA诊断日本活体供肾移植受者的亚临床排斥反应:一项多中心研究试点研究
Toshihito Hirai,Taro Banno,Kazuya Omoto et al.
Toshihito Hirai et al.
Background: Donor-derived cell-free DNA (dd-cfDNA) offers a non-invasive biomarker for detecting allograft injury. However, its performance in predominantly living-donor transplant settings in Asian populations remains un...
Multicenter Study
Clinical transplantation. 2025 Jul;39(7):e70221. DOI:10.1111/ctr.70221 2025
Increased Donor-Derived Cell-Free DNA as a Predictor for the Early Detection of Antibody-Mediated Rejection Following Heart Transplantation [0.03%]
移植后供体来源的细胞-freeDNA增加作为早期预测抗体介导的心脏排斥反应的指标
Dana Dlouha,Sarka Chytilova,Jevgenija Vymetalova et al.
Dana Dlouha et al.
Plasma circulating donor-derived cell-free DNA (ddcfDNA) can be used to noninvasively monitor acute rejection of heart transplants (HTx). This study utilized digital droplet PCR to analyze ddcfDNA concentrations (measured in copies per mill...
Advances and challenges in the application of donor-derived cell-free DNA for diagnosis and treatment in liver transplantation: a narrative review [0.03%]
肝移植中供者来源细胞游离DNA诊断和治疗应用进展与挑战:叙事综述
Yiwu Zhong,Xu Hu,Xiaoping Li et al.
Yiwu Zhong et al.
In the field of liver disease treatment, liver transplantation (LT) has become an effective option for end-stage liver disease. However, issues such as immune rejection and graft damage remain important factors influencing the success rate ...
Absolute Quantification of Donor-Derived Cell-Free DNA Following Pediatric and Adult Heart Transplantation [0.03%]
儿童和成人心脏移植后供体来源的细胞-freeDNA的绝对定量
Jens Böhmer,Håkan Wåhlander,Karin Tran-Lundmark et al.
Jens Böhmer et al.
Objective: Traditional rejection surveillance after heart transplantation (HTx) is based on endomyocardial biopsies (EMB), which are invasive, expensive and associated with complications. Monitoring using cell-free DNA (c...
A Novel Method to Estimate Donor-Derived Cell-Free DNA in Pregnant Kidney Transplant Recipients: A Proof-of-Concept Study [0.03%]
评估怀孕肾移植受者供体来源细胞-freeDNA的新方法:概念验证研究
Jessica Tang,Lior Kashani Ligumsky,Kate Woodruff et al.
Jessica Tang et al.
Background: Pregnant kidney transplant recipients (KTRs) are a vulnerable, high-risk population, susceptible to obstetrical complications, as well as graft rejection. Current methods used to monitor kidney transplant func...
A novel INDEL-based next-generation sequencing assay for monitoring donor-derived cell-free DNA in renal transplant recipients-from bedside to results: a UK pilot study [0.03%]
基于新一代测序的INDEL检测技术在肾移植受者中监测供体来源细胞游离DNA:一项英国试点研究从床边到结果
George E Nita,Fotini Partheniou,Dan Ridgway et al.
George E Nita et al.
Background: Monitoring donor-derived cell-free DNA (dd-cfDNA) is a promising noninvasive method for assessing allograft health in renal transplant recipients. This UK pilot study evaluated a novel insertion and deletion (...
Simply measuring what matters-toward clinical utility of donor-derived cell-free DNA testing? [0.03%]
只测量重要的指标?——供者来源细胞游离DNA检测的临床应用价值展望?
Maarten Naesens,Germaine Wong
Maarten Naesens
Clinical utility of donor-derived cell-free DNA testing for kidney transplant monitoring in selected patients [0.03%]
用于供者来源细胞游离DNA检测的肾脏移植患者监测临床效用研究
Klemens Budde,Bilgin Osmanodja,Eva Schrezenmeier et al.
Klemens Budde et al.
Donor-derived cell-free DNA is associated with the degree of immunosuppression in lung transplantation [0.03%]
供体来源的细胞游离DNA与肺移植免疫抑制程度相关
Ananth V Charya,Moon K Jang,Hyesik Kong et al.
Ananth V Charya et al.
Donor-derived cell-free DNA is increasingly used in clinical practice to monitor lung transplant patients for acute rejection. However, its association with conventional approaches to monitor immunosuppression remains unclear. This multicen...
Implementation of the in-house technique for the determination of donor-derived cell-free DNA in daily clinical practice: Experience from the Hospital Clinic of Barcelona [0.03%]
巴塞罗那克利诊所常规临床实践中的供体来源细胞游离DNA检测方法及其应用经验
Elena Cuadrado-Payán,Eva González-Roca,Diana Rodríguez-Espinosa et al.
Elena Cuadrado-Payán et al.
Background and objective: The introduction of donor-derived free DNA (ddcfDNA) has emerged as an accurate non-invasive biomarker to diagnose rejection, compared to classical ones. Here we evaluate our experience after its...
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