The prognostic potential of RNA in stage II colon cancer: Insights from a screened multicenter population-based cohort study [0.03%]
II期结肠癌中RNA的预后价值:来自一项基于人群的多中心筛查队列研究的新见解
Ulrik Korsgaard,Maria P Kristensen,Juan L García-Rodríguez et al.
Ulrik Korsgaard et al.
The management of stage II colon cancer poses an important clinical challenge due to difficulties in identifying patients at risk of recurrence. RNA expression profiles in solid tissues have demonstrated a strong potential as prognostic mar...
Identification and external validation of tumor DNA methylation panel for the recurrence risk stratification of stage II colon cancer [0.03%]
结肠癌肿瘤DNA甲基化标记的识别及外部验证以对II期结肠癌复发风险进行分层分析
Tanwei Yuan,Dominic Edelmann,Víctor Moreno et al.
Tanwei Yuan et al.
Background: Tailoring surveillance and treatment strategies for stage II colon cancer (CC) after curative surgery remains challenging, and personalized approaches are lacking. We aimed to identify a gene methylation panel...
Prognostic value of tumor-stroma ratio in a screened stage II colon cancer population: intratumoral site-specific assessment and tumor budding synergy [0.03%]
肿瘤间质比在筛查的二期结肠癌人群中的预后价值:瘤内部位特异性评估和肿瘤芽协同作用
Maria Pihlmann Kristensen,Ulrik Korsgaard,Signe Timm et al.
Maria Pihlmann Kristensen et al.
The tumor-stroma ratio (TSR) has shown prognostic value in various cancers, including colon cancer. This retrospective, multicenter cohort study aimed to investigate the prognostic value of TSR in a screened stage II colon cancer population...
Survival benefit of adjuvant chemotherapy in stage II large (≥5 cm) colonic adenocarcinomas: A propensity-score matched analysis [0.03%]
大肿块(≥5cm)二期结肠癌辅助化疗带来生存获益的倾向性评分匹配分析
Sameh Hany Emile,Nir Horesh,Zoe Garoufalia et al.
Sameh Hany Emile et al.
Background: Current guidelines recommend selective adjuvant chemotherapy for stage II colon cancer with high-risk features. This study aimed to assess survival benefit of adjuvant chemotherapy in patients with stage II co...
Frank A Sinicrope
Frank A Sinicrope
Rates of adjuvant chemotherapy in patients with early-onset versus later-onset stage II colon cancer.
Treatments and clinical outcomes in stage II colon cancer patients with 12-gene Oncotype DX Colon Recurrence Score® assay-guided therapy: real-world data [0.03%]
基于Oncoype DX Colon Recurrence Score基因12重检测的Ⅱ期结肠癌患者治疗及预后的实证研究数据
B Brenner,K Shulman,A Hubert et al.
B Brenner et al.
Background: The 12-gene Oncotype DX Colon Recurrence Score® result quantifies the recurrence risk in stage II/III colon cancer (CC). This real-world study investigated stage II CC patients whose treatment decisions incor...
Tumour Budding Is a Useful Predictor to Identify High-Risk Stage II Colon Cancer Patients After Curative Surgery [0.03%]
肿瘤芽生现象可有效识别出根治术后高危II期结肠癌患者
Mehmet Zengin,Özlem Tanas Işıkçı
Mehmet Zengin
Aim. Although it is now accepted in the literature that tumour budding (TB) is a useful survival indicator in colon cancer (CC), there are still uncertainties about daily use. Here we methodologically examined the role of TB on survival in ...
Exploring prognostic values of DNA ploidy, stroma-tumor fraction and nucleotyping in stage II colon cancer patients [0.03%]
探索DNA倍体、肿瘤间质比例和核型分析在II期结肠癌患者预后价值
Yutong Lou,Lujing Yang,Shaojun Xu et al.
Yutong Lou et al.
Purpose: To assess the prognostic value of three novel biomarkers, DNA ploidy, stroma-tumor fraction, and nucleotyping, seeking for more accurate stratification in stage II colon cancer. ...
Survival Outcomes in Patients with Monobloc-Resected Stage IIC (pT4bN0) Colon Cancer: A Retrospective Observational Cohort Study [0.03%]
一期C期(pT4bN0)结直肠癌单块切除患者预后:一项回顾性队列研究
Juliette Logeart,Thomas Samaille,Antoine Falcoz et al.
Juliette Logeart et al.
Background: Stage II colon cancer (CC) exhibits considerable prognostic heterogeneous. Our objective was to assess survival but also the prognosis impact of microsatellite instability (MSI) in patients with stage IIC (T4b...
Complete Obstruction, a Real Risk Factor: A Comprehensive Study on Obstruction in Stage IIA Colon Cancer With Propensity Score Matching Analysis [0.03%]
完全性梗阻,不容忽视的风险因素——结合倾向评分匹配分析的结肠癌IIA期手术患者术后并发症的全面研究
Soo Young Oh,Chan Wook Kim,Seonok Kim et al.
Soo Young Oh et al.
Microabstract: This study evaluates the prognostic significance of obstructions in stage IIA colon cancer, distinguishing between partial and complete obstructions. It employs a retrospective review of 1914 patients with ...
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