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Denis Burdakov,Daria Peleg-Raibstein Denis Burdakov
Memory is a complex and multifaceted cognitive function integral to all aspects of survival across species. It involves short-term and long-term components, which are supported by distinct yet interconnected brain systems, each specialized ...
Jens Mittag,Beke Kolms Jens Mittag
As evidenced by the clinical symptoms in hyper- or hypothyroidism, thyroid hormones have strong effects on cardiovascular and metabolic functions. While these actions had been initially attributed to direct molecular mechanisms in the respe...
Anita Torossian,Blake A Miranda,Fernando McV Reis et al. Anita Torossian et al.
Flexible experience-dependent learned escape has paramount survival value. However, flight is generally investigated in the presence of innate threats. To study conditioned escape, we developed a paradigm in which mice learn to escape a mov...
Jena S Marsh,Cara Teixeira,Swapnil Gavade et al. Jena S Marsh et al.
Avoidance or anxiety-like behavior is accompanied by corresponding changes in hypothalamic-pituitary-adrenal (HPA) axis activation. The underlying neural circuitry for this coordinated behavioral and neuroendocrine control is not well estab...
Emily O Staricoff,Mark L Evans Emily O Staricoff
Maintenance of normal blood glucose is important for survival. In particular, brain function is dependent on circulating glucose. In health, a series of powerful counterregulatory defences operate to prevent/limit hypoglycaemia. These defen...
Martin J Kelly,Edward J Wagner Martin J Kelly
Recent molecular biological and electrophysiological studies have identified multiple transient receptor potential (TRP) channels in hypothalamic neurons as critical modulators of homeostatic functions. In particular, the canonical transien...
Roberto Salvatori,Gary L Gallia Roberto Salvatori
Jonathan Q Purnell,Carel W le Roux Jonathan Q Purnell
Background: Hypothalamic centres have been recognized to play a central role in body weight regulation for nearly 70 years. Aims: In th...
Long Mei,Takuya Osakada,Dayu Lin Long Mei
Sexual, parental, and aggressive behaviors are central to the reproductive success of individuals and species survival and thus are supported by hardwired neural circuits. The reproductive behavior control column (RBCC), which comprises the...
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