Mechanism of ATP hydrolysis in the Hsp70 BiP nucleotide-binding domain [0.03%]
BiP的Hsp70二聚体结合结构域的ATP水解机制
Guillaume Mas,Sebastian Hiller
Guillaume Mas
The 70 kDa heat shock protein (Hsp70) family of molecular chaperones ensures protein biogenesis and homeostasis, driven by ATP hydrolysis. Here, we introduce in-cyclo NMR, an experimental setup that combines high-resolution NMR spectroscopy...
Impaired ATP hydrolysis in blood plasma contributes to age-related neutrophil dysfunction [0.03%]
血液等离子体中受损的ATP水解作用导致年龄相关的中性粒细胞功能障碍
Carola Ledderose,Eleftheria-Angeliki Valsami,Mark Elevado et al.
Carola Ledderose et al.
Background: The function of polymorphonuclear neutrophils (PMNs) decreases with age, which results in infectious and inflammatory complications in older individuals. The underlying causes are not fully understood. ATP rel...
Nadia Elghobashi-Meinhardt
Nadia Elghobashi-Meinhardt
Differential regulation of ATP hydrolysis of RIG-I-like receptors by transactivation response RNA-binding protein [0.03%]
转录激活反应RNA结合蛋白对RIG-I样受体ATP水解的差异化调控
Benyapa Chunhaphinyokul,Emi Hosokai,Masahiko Miyamoto et al.
Benyapa Chunhaphinyokul et al.
Retinoic acid inducible gene (RIG)-I-like receptors (RLRs), including RIG-I, melanoma differentiation associated-5 (MDA5), and laboratory of genetics and physiology 2 (LGP2), play pivotal roles in viral RNA sensing to initiate antiviral int...
Effect of extracellular adenosine triphosphate hydrolysis by apyrase on bleomycin-induced circulating and alveolar mononuclear phagocyte activation and lung inflammation [0.03%]
胞外三磷酸腺苷水解酶对博莱霉素诱导的循环和肺泡单核吞噬细胞活化及肺部炎症的影响
Chengcheng Su,Shengkun Lang,Yongqiang Ma et al.
Chengcheng Su et al.
Controllable Release Mode Based on ATP Hydrolysis-Fueled Supra-Amphiphile Assembly [0.03%]
基于ATP水解驱动的超分子两亲体聚集的可控释放模式
Di Pei,Bo Liu,Shuai Zhao et al.
Di Pei et al.
The controllable intermittent and stepwise release modes were achieved in a dissipative system of supra-amphiphile. The supra-amphiphile was constructed based on complexation of cationic amphiphile (Zn@DPA-14) and biological energy currency...
A sensor array based on DNA-wrapped bimetallic zeolitic imidazolate frameworks for detection of ATP hydrolysis products [0.03%]
基于DNA包覆的双金属咪唑酸盐框架传感器阵列用于检测三磷酸腺苷水解产物
Zhen Wang,Xumei Zhou,Zhicheng Huang et al.
Zhen Wang et al.
Most current biosensors were designed for the detection of individual analytes, or a group of chemically similar analytes. We reason that sensors designed to track both reactants and products might be useful for following chemical reactions...
Spectroscopic glimpses of the transition state of ATP hydrolysis trapped in a bacterial DnaB helicase [0.03%]
细菌DnaB解旋酶中三磷酸腺苷水解过渡态的光谱学窥探
Alexander A Malär,Nino Wili,Laura A Völker et al.
Alexander A Malär et al.
The ATP hydrolysis transition state of motor proteins is a weakly populated protein state that can be stabilized and investigated by replacing ATP with chemical mimics. We present atomic-level structural and dynamic insights on a state crea...
Cerium(iii)-directed assembly of glutathione-capped gold nanoclusters for sensing and imaging of alkaline phosphatase-mediated hydrolysis of adenosine triphosphate [0.03%]
氯磷酸酶介导的三磷酸腺苷水解检测及成像的谷胱甘肽封端金纳米团簇传感器的构建与发展
Jyun-Guo You,Chi-Yu Lu,A Santhana Krishna Kumar et al.
Jyun-Guo You et al.
Aggregation-induced emission enhancement (AIEE) of thiolated gold nanoclusters (AuNCs) has emerged as an attractive and alternative strategy to improve their brightness. This study demonstrates Ce(iii)-triggered AIEE of glutathione-capped A...
Boosted coupling of ATP hydrolysis to substrate transport upon cooperative estradiol-17-β-D-glucuronide binding in a Drosophila ATP binding cassette type-C transporter [0.03%]
合作绑定的雌二醇-17-β-D-葡萄糖醛酸盐能增强果蝇ATP结合盒型-C转运蛋白中底物运输与ATP水解的耦合效应
Agnes Karasik,Kaitlyn Victoria Ledwitch,Tamás Arányi et al.
Agnes Karasik et al.
ATP binding cassette type-C (ABCC) transporters move molecules across cell membranes upon hydrolysis of ATP; however, their coupling of ATP hydrolysis to substrate transport remains elusive. Drosophila multidrug resistance-associated protei...
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