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Chiara Trevisan,Amber Hadermann,Stephen Raimon Jada et al. Chiara Trevisan et al.
Background: Onchocerciasis, a neglected tropical disease (NTD) caused by Onchocerca volvulus, is hyperendemic in many parts of Africa, including South Sudan. Pregnant women may be a parasite reservoir as they are not incl...
John B Patton,Sasisekhar Bennuru,Mark L Eberhard et al. John B Patton et al.
Background: The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection. Small animal models that support the devel...
Irene Ajonina-Ekoti,Marc Andre Kurosinski,Abuelhassan Elshazly Younis et al. Irene Ajonina-Ekoti et al.
The macrophage migration inhibitory factors (MIFs) from the filarial parasite Onchocerca volvulus (OvMIF) were compared to the MIFs from the free-living nematode Caenorhabditis elegans (CeMIF) with respect to molecular, biochemical and immu...
Mario A Rodríguez-Pérez,Bruce G Lilley,Alfredo Domínguez-Vázquez et al. Mario A Rodríguez-Pérez et al.
To investigate the impact of mass ivermectin treatments in Mexico on Onchocerca volvulus transmission, entomologic surveys were carried out in the two endemic states of Oaxaca and Chiapas. The data suggest that substantial progress towards ...
C Holst,P F Zipfel C Holst
Eukaryotic transcription factors can be identified and classified according to conserved DNA-binding motifs and conserved regulatory domains. The functional and structural analysis, and the conservation of these genes among metazoans emphas...
R Chandrashekar,A F Ogunrinade,R W Henry et al. R Chandrashekar et al.
Improved methods for diagnosis of onchocerciasis are needed. We have recently identified immune complex-associated parasite antigens in sera from onchocerciasis patients. The goal of this study was to produce monoclonal antibodies to these ...
H Fuglsang,J Anderson,T F de C Marshall et al. H Fuglsang et al.
Repeated multiple skin snips in 18 persons with onchocerciasis from the Sudan-savanna of West Africa suggested the possibility of a seasonal variation in microfilarial concentrations. This variation may be an evolutionary adaptation of the ...