Pregnant Women, a Potential Reservoir for Onchocerca volvulus? A Cross Sectional Study in Maridi County, South Sudan [0.03%]
南苏丹马里迪县的一项横断面研究:怀孕妇女会成为盘尾丝虫的潜在载体吗?
Chiara Trevisan,Amber Hadermann,Stephen Raimon Jada et al.
Chiara Trevisan et al.
Background: Onchocerciasis, a neglected tropical disease (NTD) caused by Onchocerca volvulus, is hyperendemic in many parts of Africa, including South Sudan. Pregnant women may be a parasite reservoir as they are not incl...
Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum [0.03%]
人源化NSG小鼠中的旋毛纲卷曲丝虫病的发病过程及其尿液和血清寄生虫生物标志物的检测
John B Patton,Sasisekhar Bennuru,Mark L Eberhard et al.
John B Patton et al.
Background: The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection. Small animal models that support the devel...
Comparative analysis of macrophage migration inhibitory factors (MIFs) from the parasitic nematode Onchocerca volvulus and the free-living nematode Caenorhabditis elegans [0.03%]
寄生线虫Onchocerca volvulus和自由生活的线虫Caenorhabditis elegans的巨噬细胞迁移抑制因子(MIFs)的比较分析
Irene Ajonina-Ekoti,Marc Andre Kurosinski,Abuelhassan Elshazly Younis et al.
Irene Ajonina-Ekoti et al.
The macrophage migration inhibitory factors (MIFs) from the filarial parasite Onchocerca volvulus (OvMIF) were compared to the MIFs from the free-living nematode Caenorhabditis elegans (CeMIF) with respect to molecular, biochemical and immu...
Comparative Study
Parasitology research. 2013 Sep;112(9):3335-46. DOI:10.1007/s00436-013-3513-1 2013
Polymerase chain reaction monitoring of transmission of Onchocerca volvulus in two endemic states in Mexico [0.03%]
墨西哥两个流行州引起河盲症的盘尾丝虫病的传播监测(聚合酶链反应)
Mario A Rodríguez-Pérez,Bruce G Lilley,Alfredo Domínguez-Vázquez et al.
Mario A Rodríguez-Pérez et al.
To investigate the impact of mass ivermectin treatments in Mexico on Onchocerca volvulus transmission, entomologic surveys were carried out in the two endemic states of Oaxaca and Chiapas. The data suggest that substantial progress towards ...
C Holst,P F Zipfel
C Holst
Eukaryotic transcription factors can be identified and classified according to conserved DNA-binding motifs and conserved regulatory domains. The functional and structural analysis, and the conservation of these genes among metazoans emphas...
Onchocerca volvulus: monoclonal antibodies to immune complex-associated parasite antigens [0.03%]
盘尾丝虫(免疫复合物有关的寄生虫抗原的单克隆抗体)
R Chandrashekar,A F Ogunrinade,R W Henry et al.
R Chandrashekar et al.
Improved methods for diagnosis of onchocerciasis are needed. We have recently identified immune complex-associated parasite antigens in sera from onchocerciasis patients. The goal of this study was to produce monoclonal antibodies to these ...
Seasonal variation in the concentration of Onchocerca volvulus microfilariae in the skin? [0.03%]
皮肤中盘尾丝虫微丝蚴密度的季节性变化?
H Fuglsang,J Anderson,T F de C Marshall et al.
H Fuglsang et al.
Repeated multiple skin snips in 18 persons with onchocerciasis from the Sudan-savanna of West Africa suggested the possibility of a seasonal variation in microfilarial concentrations. This variation may be an evolutionary adaptation of the ...