External validation of FRISBEE 2-year and 5-year fracture prediction models in a fracture liaison service cohort [0.03%]
基于骨折联络服务队列对FRISBEE 2年和5年骨折预测模型的外部验证研究
Tove T Borgen,Cathrine Brunborg,Frede Frihagen et al.
Tove T Borgen et al.
We externally validated the FRISBEE models of 2-year and 5-year fracture risk prediction in 517 women with index fractures. Both models overestimated the fracture risk. Recalibration of the FRISBEE models are needed before use in Norwegian ...
Pharmacokinetic variability of 20(S)-protopanaxadiol-type ginsenosides Rb1, rd, and compound K from Korean red ginseng in experimental rodents [0.03%]
人参皂苷Rb1、rd和Compound K型在实验动物中的药动学变异
Ji-Soo Jeong,Jeong-Won Kim,Jin-Hwa Kim et al.
Ji-Soo Jeong et al.
Korean red ginseng (KRG, Panax ginseng C.A. Meyer) contains ginsenosides, which are metabolized into active metabolites with various pharmacological effects. This study assessed the in vivo exposure and accumulation of ginsenosides followin...
Ansa E Cobham,Alexander Kenzior,Pedro Morales-Sosa et al.
Ansa E Cobham et al.
All animals age, but the rate of aging across species varies widely. The environmental pressures and molecular factors underlying this remarkable diversity in aging across species remains largely enigmatic. The Mexican tetra, Astyanax mexic...
Structural convergence and water-mediated substrate mimicry enable broad neuraminidase inhibition by human antibodies [0.03%]
结构收敛和水介导的底物模拟使人类抗体能够广泛抑制神经氨酸酶
Julia Lederhofer,Andrew J Borst,Lam Nguyen et al.
Julia Lederhofer et al.
Influenza has been responsible for multiple global pandemics and seasonal epidemics and claimed millions of lives. The imminent threat of a panzootic outbreak of avian influenza H5N1 virus underscores the urgent need for pandemic preparedne...
Outcomes for single antiplatelet, dual antiplatelet, or oral anticoagulation after Amulet: Insights from EMERGE LAA post-approval study [0.03%]
单用抗血小板药物、双联抗血小板药物或口服抗凝药在Amulet后的结局：EMERGE左心耳封堵器后注册研究的启示
Atman P Shah,James V Freeman,Mohamad Alkhouli et al.
Atman P Shah et al.
Background: Outcomes associated with different antithrombotic strategies after Amulet left atrial appendage occlusion (LAAO) are not well described. Objec...
Indirect Comparison of Linvoseltamab Versus Teclistamab for the Treatment of Triple-Class Exposed Relapsed/Refractory Multiple Myeloma [0.03%]
利夫珠单抗与泰菲妥莫单抗治疗三线及以上复发难治多发性骨髓瘤的间接对比研究
Hans C Lee,Naresh Bumma,Joshua Richter et al.
Hans C Lee et al.
Background: B-cell maturation antigen (BCMA) bispecific antibodies have advanced treatment of relapsed/refractory multiple myeloma (RRMM), but comparative data are lacking. ...
Jason E Liebowitz
Jason E Liebowitz
Surface-specific outcomes of mechanical debridement with titanium, chitosan and nitinol brushes on titanium dental implant surfaces [0.03%]
基于钛、壳聚糖和镍钛丝牙刷对钛种植体表面机械清创的特异性效果研究
Angela De Lauretis,Marco Santacroce,Jan Eirik Ellingsen et al.
Angela De Lauretis et al.
Objectives: Dental implants are susceptible to peri-implant inflammation caused by bacterial biofilms, with surface properties playing a key role in bacterial adhesion and osseointegration. While mechanical debridement is...
Genome-Wide Analysis and Longitudinal Study of Klebsiella pneumoniae in Portugal: Tracing the Evolution and Spread of Carbapenem Resistance [0.03%]
葡萄牙肺炎克雷伯菌的全基因组分析和纵向研究：碳青霉烯耐药性的进化与传播追溯
Rita Elias,Jody E Phelan,Luís Lito et al.
Rita Elias et al.
Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) has high incidence in Portugal, causing severe and often fatal infections. Objectives: ...
Comparisons of optimal medical treatment between men and women in patients with lower extremity peripheral artery disease and exertional limb symptoms [0.03%]
下肢外周动脉疾病劳力性间歇性跛行男女患者最佳治疗比较研究
Yasmine Semaoui,Adelaïde Guézais,Marjolaine Talbot et al.
Yasmine Semaoui et al.
Purpose: Patients with lower extremity peripheral artery disease (PAD) are undertreated with women being less likely than men to receive the optimal medical treatment (OMT). The main objective was to compare the prescript...
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