20(S)-protopanaxadiol enhances temozolomide responsiveness in MGMT-expressing glioblastoma: Wnt/β-catenin attenuation and MGMT downregulation
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Background: Glioblastoma is a highly aggressive primary brain malignancy, and O6-methylguanine-DNA methyltransferase (MGMT)-mediated DNA repair contributes to reduced temozolomide (TMZ) responsiveness. This study investigated whe... ...
