Structural Determinants of Zn2+ Potentiation of Gingipain B Inhibition of Porphyromonas gingivalis by Compounds With the Benzamidine Group: A Computational Study
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Gingipain B is a protease released by Porphyromonas gingivalis, which contributes to the development of diseases such as periodontitis, Alzheimer's disease, rheumatoid arthritis and cancer. Therefore, it could be a key target for the design of inhibitors that... ...