Enhancing Bioavailability of Ultra-High Concentration Antibody Formulations Using Ionic Liquids
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Subcutaneous (SC) delivery of ultra-high concentration antibody formulations (uHCAFs, > 150 mg/mL) is limited by excessive viscosity and poor bioavailability. Here, we present an ionic liquid made with choline and tryptophan (CHAT) as a multifunctional excipie... ...