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KDM4A promotes microglial pyroptosis and neuropathic pain via the MEG3/SMURF2/HES1 axis

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Neuropathic pain (NP) is a refractory clinical disorder in which microglial pyroptosis plays a crucial role, yet the epigenetic regulation by lysine demethylase 4A (KDM4A) remains unclear. In this study, chronic constriction injury (CCI) rat models were establ... ...