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Type I interferon-activated myeloid states are associated with less fibrotic stages in idiopathic pulmonary fibrosis

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Early immune processes in idiopathic pulmonary fibrosis (IPF) are poorly defined. Here, we integrate single-cell transcriptomics of lung digests and bronchoalveolar-lavaged cells (n = 108 patients), subcellular-resolution tissue spatial transcriptomics, and si... ...