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Comparative proteomic analysis of the angiogenic response in an in vitro model of vascular endothelial cells to excretory/secretory and somatic antigens of Dirofilaria immitis

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Background: Dirofilaria immitis infection induces endothelial inflammation and vascular remodeling, contributing to heartworm disease pathology. While excretory/secretory antigens (DiES) are known to promote angiogenesis, somatic... ...