G protein-coupled receptor kinase 3 regulates CCR7 signaling, trafficking, and T cell responses to CCL19 and CCL21
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G protein-coupled receptors (GPCRs) can bind multiple ligands leading to differential signaling events termed biased signaling. GPCR kinases (GRKs) can control the phosphorylation patterns of a GPCR to regulate biased signaling. Since the functions of GRKs are... ...