Mechanical loading under estrogen deficiency enhances mineralization and osteoblast maturation in an advanced 3D vascularized bone organoid driven by hypertrophy and apoptosis
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Bone is a highly mechanosensitive tissue that responds to mechanical cues and adapts to maintain a homeostatic balance between bone formation and resorption, thereby preserving structural integrity and strength. Estrogen is the key modulator of skeletal homeos... ...
