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Sulfonyl-substituted zinc phthalocyanine micelles with long-lived triplet states enable durable photodynamic immunotherapy

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Pluronic® P123 micelles stabilized a sulfonyl-substituted zinc(ii) phthalocyanine, prolonged its triplet-state lifetime, and preserved ROS photochemistry under biologically relevant conditions. Pharmacokinetic-guided C-PDT at a 24 h DLI remained insufficient ... ...