Mechanisms contributing to the age at onset of temporal lobe epilepsy due to hippocampal sclerosis
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Temporal lobe epilepsy (TLE) secondary to hippocampal sclerosis (HS) is a common cause of drug-resistant epilepsy. HS is characterized by neuronal loss in selected hippocampal subfields and gliosis. Age at epilepsy onset (AEO) critically influences disease sev... ...