DHHC21 is a STIM1 protein S-acyltransferase that modulates immune function in vivo
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Depletion of Ca2+ from ER stores leads to the activation of Ca2+ channels on the plasma membrane known as store-operated Ca2+ entry. The proteins STIM1 and STIM2 function as ER Ca2+ sensors, and upon store depletion, they undergo a conformational change that a... ...
