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Succinate and its carrier Sfc1 mediate metabolic control of mitochondrial protein import by the TIM23 translocase

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Tim23 is an essential component of the mitochondrial inner membrane translocase and Sfc1 is a carrier that exchanges succinate for fumarate across that membrane. Sfc1 and succinic acid availability regulate dual targeting of fumarase and aconitase by facilitat... ...