Metabolomics fingerprinting identifies redox-dependent inhibition of TXNIP alleviates renal fibrosis via modulation of TGF-β1/COL-1/ GRP78 signaling axis in a diabetic nephropathy rat model
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Diabetic nephropathy (DN) is a chronic metabolic disorder characterized by hyperglycaemia-induced disruption of renal homeostasis. Emerging evidence suggests that the TRX/TXNIP axis mediates oxidative stress and inflammation in DN. However, its specific role i... ...
