PTPN1 and PTPN2 cooperatively set interferon responsiveness thresholds that govern cancer immune evasion
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Immune evasion by cancer cells remains a major barrier to the success of immune checkpoint blockade (ICB). In recent years, Protein tyrosine phosphatase non-receptor type 2 (PTPN2) has emerged as a promising and druggable target for cancer immunotherapy. Small... ...
