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Kmt2c and Kmt2d histone methyltransferase deficiencies compromise macrophage function

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Methylation of histone (H) 3 lysine (K) 4 has a well-established role in innate immune responses, but the contribution of H3K4 methyltransferases Kmt2c and Kmt2d in innate immunity is incompletely understood. Using conditional knockout (KO) mouse models, we in... ...