Astragalus polysaccharides ameliorate ulcerative colitis by targeting the HMGB1/TLR4 signaling axis to inhibit neutrophil extracellular trap formation
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Purpose: Ulcerative colitis (UC) pathogenesis involves neutrophil extracellular trap (NET) formation and intestinal barrier collapse. High mobility group box 1 (HMGB1) acts as a critical "alarmin," triggering neutrophil activat... ...
