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The prognostic potential of circulating BDNF levels and its polymorphisms in age-related cognitive impairment and neurodegeneration

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Brain-derived neurotrophic factor (BDNF) is essential for neuronal survival, synaptic plasticity, and cognitive function. Age-related decline in BDNF signaling has been implicated in the pathogenesis of Alzheimer's disease, Parkinson's disease, and mild cogn... ...