Regulation of oestrogen signalling by the receptor tyrosine kinase cKIT stabilises the Barrett's Oesophagus pre-malignant state
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The pre-malignant precursor to oesophageal adenocarcinoma (OAC), Barrett's Oesophagus (BO), is prevalent in 10-15% of patients with chronic gastroesophageal acid reflux. However, in most cases the Barrett's Oesophagus condition is stable to cancer promotion,... ...
