PIP4K2A depletion suppresses AKT signaling and enhances chemotherapy sensitivity in T-cell lymphoblastic lymphoma cells
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T-cell lymphoblastic lymphoma (T-LBL) is an aggressive malignancy of immature T cells characterized by rapid proliferation and frequent activation of pro-survival pathways such as PI3K/AKT/mTORC1 signaling. Although multi-agent chemotherapy can induce remissio... ...
