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The many facets of Kaposi sarcoma-associated herpesvirus/human herpes virus-8 multicentric Castleman disease: clinical spectrum, diagnostic innovations, and therapeutic management

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Background: Castleman diseases encompass three distinct entities: unicentric Castleman disease, KSHV/HHV-8-associated multicentric Castleman disease (MCD), and idiopathic MCD. HHV-8 MCD is a life-threatening B-cell lymphoprolifer... ...