miR-1a-3p impairs β-cell function in male offspring via disrupted NBR1-dependent mitochondrial function but not apoptosis after maternal high-saturated-fat diet in mice
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Early-life maternal high-saturated fat (HSF) exposure increases offspring susceptibility to type 2 diabetes, but mechanisms linking it to β-cell dysfunction remain poorly defined. This study aimed to identify key miRNAs mediating this programming and evaluate... ...