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Exogenous matrix-free biomanufacturing of glioblastoma organoids enables autonomous assembly of neurovascular-like structures and extracellular matrix

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Current glioblastoma (GBM) models often rely on chemically undefined exogenous extracellular matrices (ECMs) and serums that limit understanding of autonomous cellular behaviors driving tumor progression. Here, we present an exogenous ECM-free biomanufacturing... ...